Evidence map›Paper›PMID 31887795›Full record

ArticleYonsei medical journal2020

Increased Progastrin-Releasing Peptide Expression is Associated with Progression in Gastric Cancer Patients.

Li Li, Xiaodong Yin, Hai Meng, Juanyu Hu, Zhengqing Yu, Jianyong Xu

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of hormones on intestinal stem cells.Stem cell research & therapy · 2023
    Review
  4. Association between Serum Progastrin Biomarker Level and Gastric Cancer.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Li Li *Department of Clinical Laboratory, Binhai County People's Hospital, Jiangsu, China. lili5898@126.com.ORCID https://orcid.org/0000-0003-0935-8634
Xiaodong Yin *Department of Medical Oncology, Binhai County People's Hospital, Jiangsu, China.ORCID https://orcid.org/0000-0003-0921-6257
Hai MengDepartment of Gastroenterology, Binhai County People's Hospital, Jiangsu, China.ORCID https://orcid.org/0000-0002-9500-8085
Juanyu HuDepartment of Clinical Laboratory, Binhai County Second Hospital, Jiangsu, China.ORCID https://orcid.org/0000-0001-7251-8624
Zhengqing YuDepartment of Clinical Laboratory, Binhai County People's Hospital, Jiangsu, China.ORCID https://orcid.org/0000-0001-8185-3758
Jianyong XuDepartment of Clinical Laboratory, Binhai County People's Hospital, Jiangsu, China.ORCID https://orcid.org/0000-0003-1910-4603
Binzhou People's Hospital · CNNanjing Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to assess the diagnostic and prognostic value of serum progastrin-releasing peptide (ProGRP) in patients with gastric cancer (GC). MATERIALS AND

methodsA total of 150 patients with GC (89 males and 61 females) were recruited, including those with stage I (n=28), stage II (n=33), stage III (n=50), and stage IV (n=39) disease; 50 healthy controls and 66 patients with benign gastric diseases were also enrolled. Levels of serum ProGRP, carcinoembryonic antigen (CEA), and carbohydrate antigen 72-4 (CA72-4) were measured in all subjects.

resultsSerum ProGRP levels were significantly higher in GC patients than in controls (

conclusionProGRP may be useful as a potential biomarker for GC diagnosis and therapy.

Indexed as

Disease ProgressionAdultAgedAntigens, Tumor-Associated, CarbohydrateBiomarkers, TumorCarcinoembryonic AntigenCase-Control StudiesFemaleGPI-Linked ProteinsHumansMaleMiddle AgedPeptide FragmentsPrognosisRecombinant ProteinsROC CurveAntigens, Tumor-Associated, CarbohydrateBiomarkers, TumorCA-72-4 antigenCarcinoembryonic AntigenCEACAM5 protein, humanGPI-Linked ProteinsPeptide Fragmentspro-gastrin-releasing peptide (31-98)Recombinant Proteinsgastric cancerProgastrin-releasing peptideprogression

Identifiers

PMID31887795
PMCPMC6938777
OpenAlexW2998663519

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.