Evidence map›Paper›PMID 31892855›Full record

ArticleInternational journal of biological sciences2020

GATA Binding Protein 4 Regulates Tooth Root Dentin Development

Yuxin Zhang, Mengru Fang, Zhiwen Yang, Wenhao Qin, Shuyu Guo, Junqing Ma, Wenjing Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Ablation of FAM20C caused short root defects via suppressing the BMP signaling pathway in mice.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuxin ZhangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Mengru FangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Zhiwen YangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Wenhao QinJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Shuyu GuoJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Junqing MaJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Wenjing ChenJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tooth development is a complex process that is regulated precisely by several signalling pathways and transcription factors. GATA-binding protein 4 (GATA4) is a DNA binding transcription factor, and our previous study showed that GATA4 is a novel regulator of root development. However, it remains unclear whether GATA4 is necessary for odontoblast differentiation and dentin formation. Here, we evaluated the phenotypic changes of

Indexed as

AnimalsCell DifferentiationDentinDentinogenesisFructose-BisphosphataseGATA4 Transcription FactorGluconeogenesisMice, KnockoutMultipotent Stem CellsNeural CrestOdontoblastsTooth RootFructose-BisphosphataseGata4 protein, mouseGATA4 Transcription Factordentinogenesisgluconeogenesisknockout micemultipotent stem cellsneural crestodontoblasts

Identifiers

PMID31892855
PMCPMC6930368
OpenAlexW2991777089

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.