Evidence map›Paper›PMID 31912367›Full record

ReviewJournal of cell communication and signaling2020

Regulation of bone morphogenetic protein 4 on epithelial tissue.

Sitong Shen, Shurong Wang, Yuxi He, Huicong Hu, Boyuan Yao, Yan Zhang

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cell communication and signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. The role of BMP4 in adipose-derived stem cell differentiation: A minireview.Frontiers in cell and developmental biology · 2022
    Review
  10. The Role of Bone Morphogenetic Protein 4 in Ovarian Function and Diseases.Reproductive sciences (Thousand Oaks, Calif.) · 2021
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sitong ShenDepartment of Ophthalmology, the 2nd Hospital of Jilin University, Changchun, 130041, China.
Shurong WangDepartment of Ophthalmology, the 2nd Hospital of Jilin University, Changchun, 130041, China.
Yuxi HeDepartment of Ophthalmology, the 2nd Hospital of Jilin University, Changchun, 130041, China.
Huicong HuDepartment of Ophthalmology, the 2nd Hospital of Jilin University, Changchun, 130041, China.
Boyuan YaoDepartment of Ophthalmology, the 2nd Hospital of Jilin University, Changchun, 130041, China.
Yan ZhangDepartment of Ophthalmology, the 2nd Hospital of Jilin University, Changchun, 130041, China. zhangy66@jlu.edu.cn.
Jilin University · CN

Funding

Outstanding Young Teacher Training Program of Jilin University 419080520314Science and Technology Department 20180101146JCScience and Technology Project of Jilin Traditional Chinese Medicine 2019134
6 · The paper itself

Abstract

Epithelial tissues provide tissue barriers and specialize in organs and glands. When epithelial homeostasis is physiologically or pathologically stimulated, epithelial cells produce mesenchymal cells through the epithelial-mesenchymal transition, forming new tissues, promoting the cure of diseases or leading to illness. A variety of cytokines are involved in the regulation of epithelial cell differentiation. Bone morphogenetic proteins (BMPs), especially the bone morphogenetic protein 4 (BMP4) has a variety of biological functions and plays a prominent role in the regulation of epithelial cell differentiation. BMP4 is an important regulatory factor of a series of life activities in vertebrates, which is also related to cell proliferation, differentiation and mobility, it also has relation with tumor development. This paper mainly reviews the mechanism of BMP4's regulation on epithelial tissues, as well as its effect on the growth, differentiation, benign lesions and malignant lesions of epithelial tissues, and expounds the function of BMP4 in epithelial tissues, to provide theoretical support for the research on reducing epithelial diseases.

Indexed as

Benign lesionsBone morphogenetic protein 4CancerEpithelial tissueGrowth and differentiation

Identifiers

PMID31912367
PMCPMC7511498
OpenAlexW2998749273

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.