Evidence map›Paper›PMID 31915214›Full record

ArticlemSphere2020

Weak Acid Resistance A (WarA), a Novel Transcription Factor Required for Regulation of Weak-Acid Resistance and Spore-Spore Heterogeneity in Aspergillus niger.

Ivey A Geoghegan, Malcolm Stratford, Mike Bromley, David B Archer, Simon V Avery

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ivey A GeogheganSchool of Life Sciences, University of Nottingham, University Park, Nottingham, United Kingdom.
Malcolm StratfordSchool of Life Sciences, University of Nottingham, University Park, Nottingham, United Kingdom.
Mike BromleyDivision of Infection, Immunity & Respiratory Medicine, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.
David B ArcherSchool of Life Sciences, University of Nottingham, University Park, Nottingham, United Kingdom.
Simon V AverySchool of Life Sciences, University of Nottingham, University Park, Nottingham, United Kingdom simon.avery@nottingham.ac.uk.
University of Nottingham · GBUniversity of Manchester · GB

Funding

UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7M
MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIST32AI007323 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peter John Bradley · 1988 to 2026
$8.6M
Biochemical and Functional Analysis of TrypaninR01AI052348 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2002 to 2023
$7.4M
PREDOCTORAL TRAINING PROGRAM IN GENETIC MECHANISMS AT UCT32GM007104 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GOBER, JAMES W · 1985 to 2011
$3.6M
Social Motility and inter-kingdom interactions in African trypanosomesR21AI133166 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2018 to 2019
$410k
Biochemical and Functional Analysis of TrypaninR56AI052348 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2007 to 2007
$374k
Social Motility and cAMP signaling in chemotaxis and parasite-vector interactions of African trypanosomesR21AI142544 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2019 to 2020
$187k
Identification of factors contributing to group behavior in African TrypanosomesF31AI085961 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOPEZ, MIGUEL AUGUSTO · 2011 to 2012
$67k
Biotechnology and Biological Sciences Research Council BB/N017129/1NIAID NIH HHS F31 AI085961NIAID NIH HHS R01 AI052348NIAID NIH HHS R21 AI133166NIAID NIH HHS R21 AI142544NIAID NIH HHS R56 AI052348NIAID NIH HHS T32 AI007323NIGMS NIH HHS T32 GM007104NIGMS NIH HHS T32 GM007185Wellcome TrustWellcome Trust 208396/Z/17/Z
6 · The paper itself

Abstract

Propionic, sorbic, and benzoic acids are organic weak acids that are widely used as food preservatives, where they play a critical role in preventing microbial growth. In this study, we uncovered new mechanisms of weak-acid resistance in molds. By screening a library of 401 transcription factor deletion strains in

Indexed as

AcidsAspergillus nigerDrug Resistance, FungalFungal ProteinsGene Expression Regulation, FungalMicrobial Sensitivity TestsSaccharomyces cerevisiaeSpores, FungalTranscription FactorsAcidsFungal ProteinsTranscription FactorsAspergillusfood spoilagefungitranscription factorsweak-acid resistance

Identifiers

PMID31915214
PMCPMC6952191
OpenAlexW2999907786

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.