ReviewFrontiers in endocrinology2019
Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data.
Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 4 syntheses or guidelines pooled it, 218 citations in OpenAlex.
- Exposure to pesticides and the risk of hypothyroidism: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Early-life exposure to endocrine-disrupting chemicals and autistic traits in childhood and adolescence: a systematic review of epidemiological studies.Frontiers in endocrinology · 2023Pooled it
- Pooled it
- Interference on Iodine Uptake and Human Thyroid Function by Perchlorate-Contaminated Water and Food.Nutrients · 2020Pooled it
- Mixture Effects Investigation of a Thyroid Hormone System-Specific Interaction with Azole Fungicides.Toxics · 2026Article
- Endocrine-Disrupting Pesticides as Drivers of Human Disease: Mechanistic Toxicology and Life-Course Health Effects.International journal of molecular sciences · 2026Review
- The Thyroid Under Pressure: Heavy Metals, Endocrine Disruptors and Translational Insights into Carcinogenesis and Thyroid Dysfunctions.International journal of molecular sciences · 2026Review
- Monitoring Chemical Environmental Hazards Through Wildlife Assessment: A Review Within the "One Health" Approach.Journal of xenobiotics · 2026Review
- Influence of Artificial Light at Night on Thyroid Gland Histology inAnimals : an open access journal from MDPI · 2026Article
- Neonicotinoids: insecticides or a threat to public health?Frontiers in public health · 2026Article
- Ecological and reproductive consequences of endocrine-disrupting chemicals in agricultural systems.Reproduction & fertility · 2026Review
- Article
- Endocrine disrupting chemicals and female sexual health: An emerging research priority.Environmental research · 2025Article
- Associations between persistent organic pollutants and thyroid-related hormones and homeostasis parameters in middle-aged to older men and postmenopausal women: The HCHS/SOL.Environmental research · 2025Article
- Article
- A Comparative Study of the Effect of Commonly Used Pesticides on Cervical Contractions in Pregnant Cows, In Vitro.Toxics · 2025Article
- Pesticide exposome reveals oxidative stress and immune response disruptions in occupationally exposed women with breast cancer.Scientific reports · 2025Article
- Modulating effect of glutathione (GSH) on 2,4-dichlorophenoxyacetic acid (2,4-D) toxicity.Scientific reports · 2025Article
- Article
- Relationships of residential distance to greenhouse floriculture and organophosphate, pyrethroid, and neonicotinoid urinary metabolite concentration in Ecuadorian Adolescents.International journal of health geographics · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant Protection Products, more commonly referred to as pesticides and biocides, are used to control a wide range of yield-reducing pests including insects, fungi, nematodes, and weeds. Concern has been raised that some pesticides may act as endocrine disrupting chemicals (EDCs) with the potential to interfere with the hormone systems of non-target invertebrates and vertebrates, including humans. EDCs act at low doses and particularly vulnerable periods of exposure include pre- and perinatal development. Of critical concern is the number of pesticides with the potential to interfere with the developing nervous system and brain, notably with thyroid hormone signaling. Across vertebrates, thyroid hormone orchestrates metamorphosis, brain development, and metabolism. Pesticide action on thyroid homeostasis can involve interference with TH production and its control, displacement from distributor proteins and liver metabolism. Here we focused on thyroid endpoints for each of the different classes of pesticides reviewing epidemiological and experimental studies carried out both in
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.