Evidence map›Paper›PMID 31921812›Full record

ArticleFrontiers in bioengineering and biotechnology2019

Copy Number Variation Pattern for Discriminating MACROD2 States of Colorectal Cancer Subtypes.

ShiQi Zhang, XiaoYong Pan, Tao Zeng, Wei Guo, Zijun Gan, Yu-Hang Zhang, Lei Chen, YunHua Zhang, Tao Huang, Yu-Dong Cai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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  15. Identifying Transcriptomic Signatures and Rules for SARS-CoV-2 Infection.Frontiers in cell and developmental biology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

ShiQi ZhangSchool of Life Sciences, Shanghai University, Shanghai, China.
XiaoYong PanKey Laboratory of System Control and Information Processing, Institute of Image Processing and Pattern Recognition, Ministry of Education of China, Shanghai Jiao Tong University, Shanghai, China.
Tao ZengKey Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Wei GuoInstitute of Health Sciences, Chinese Academy of Sciences, Shanghai Jiao Tong University School of Medicine and Shanghai Institutes for Biological Sciences, Shanghai, China.
Zijun GanShanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Yu-Hang ZhangShanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Lei ChenCollege of Information Engineering, Shanghai Maritime University, Shanghai, China.
YunHua ZhangAnhui Province Key Laboratory of Farmland Ecological Conservation and Pollution Prevention, School of Resources and Environment, Anhui Agricultural University, Hefei, China.
Tao HuangShanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Yu-Dong CaiSchool of Life Sciences, Shanghai University, Shanghai, China.
Shanghai Institutes for Biological Sciences · CNShanghai University · CNAnhui Agricultural University · CNChinese Academy of Sciences · CNEast China Normal University · CNShanghai Institute of Nutrition and Health · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copy number variation (CNV) is a common structural variation pattern of DNA, and it features a higher mutation rate than single-nucleotide polymorphisms (SNPs) and affects a larger fragment of genomes. CNV is related with the genesis of complex diseases and can thus be used as a strategy to identify novel cancer-predisposing markers or mechanisms. In particular, the frequent deletions of mono-ADP-ribosylhydrolase 2 (

Indexed as

classificationcolorectal cancercopy number variationMACROD2subtype

Identifiers

PMID31921812
PMCPMC6930883
OpenAlexW2994692051

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.