Evidence map›Paper›PMID 31932898›Full record

ArticlePflugers Archiv : European journal of physiology2020

VIP and muscarinic synergistic mucin secretion by salivary mucous cells is mediated by enhanced PKC activity via VIP-induced release of an intracellular Ca

David J Culp, Z Zhang, R L Evans

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

David J CulpCenter for Oral Biology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY, 14642, USA. dculp@dental.ufl.edu.ORCID 0000-0002-2124-6347
Z ZhangCenter for Oral Biology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY, 14642, USA.
R L EvansCenter for Oral Biology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY, 14642, USA.
University of Rochester Medical Center · USUnilever (United Kingdom) · GB

Funding

SALIVARY MUCOUS CELL GENE EXPRESSIONR01DE014730 · NIDCR · UNIVERSITY OF ROCHESTER · PI CULP, DAVID JOHN · 2003 to 2007
$1.8M
REGULATION OF GLANDULAR MUCOUS CELL SECRETIONR01DE010480 · NIDCR · UNIVERSITY OF ROCHESTER · PI CULP, DAVID JOHN · 1993 to 2001
$624k
NIDCR NIH HHS DE10480 and DE014730NIDCR NIH HHS R01 DE014730
6 · The paper itself

Abstract

Mucin secretion by salivary mucous glands is mediated predominantly by parasympathetic acetylcholine activation of cholinergic muscarinic receptors via increased intracellular free calcium ([Ca

Indexed as

Adenosine TriphosphatasesAnimalsBodily SecretionsCalciumCholinergic AgentsIsoenzymesMaleMucinsMuscarinic AgonistsPhorbol EstersProtein Kinase CRatsRats, WistarReceptors, MuscarinicSalivary GlandsThapsigarginAdenosine TriphosphatasesCalciumCholinergic AgentsIsoenzymesMucinsMuscarinic Agonistsphorbol-12-myristatePhorbol EstersProtein Kinase CReceptors, MuscarinicThapsigarginVasoactive Intestinal PeptideMucinsMucous cellsSalivaSalivary glandsSignal transductions

Identifiers

PMID31932898
PMCPMC7058512
OpenAlexW2999775719

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.