Evidence map›Paper›PMID 31937813›Full record

ArticleScientific reports2020

Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics.

Mehdi Emam, Angela Cánovas, Alma D Islas-Trejo, Pablo A S Fonseca, Juan F Medrano, Bonnie Mallard

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mehdi EmamDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. semam@uoguelph.ca.ORCID http://orcid.org/0000-0001-7148-4987
Angela CánovasCentre for Genetic Improvement of Livestock, Department of Animal Biosciences, Ontario Agricultural College, University of Guelph, Guelph, Ontario, Canada.
Alma D Islas-TrejoDepartment of Animal Science, University of California-Davis, Davis, California, USA.
Pablo A S FonsecaCentre for Genetic Improvement of Livestock, Department of Animal Biosciences, Ontario Agricultural College, University of Guelph, Guelph, Ontario, Canada.
Juan F MedranoDepartment of Animal Science, University of California-Davis, Davis, California, USA.
Bonnie MallardDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
University of Guelph · CAUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive Nitrogen Species (RNS) are a group of bactericidal molecules produced by macrophages in response to pathogens in a process called oxidative burst. Nitric oxide (NO

Indexed as

TranscriptomeAnimalsCattleEscherichia coliGenomicsMacrophage ActivationMacrophagesNitric OxideNitric Oxide Synthase Type IIPhagocytosisPhenotypePolymorphism, GeneticRNA, MessengerTime FactorsTranscription FactorsNitric OxideNitric Oxide Synthase Type IIRNA, MessengerTranscription Factors

Identifiers

PMID31937813
PMCPMC6959288
OpenAlexW2999924284

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.