SynthesisJournal of applied oral science : revista FOB2020
Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis.
Synthesis in Journal of applied oral science : revista FOB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06895980 (Effect of Periodontal Treatment on Metabolic Control in Patients with Type-2 Diabetes Mellitus Treated in the Cardiovascular Healt Program), which is not on this map. Cited by 163 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Periodontal Treatment on Metabolic Control in Patients with Type-2 Diabetes Mellitus Treated in the Cardiovascular Healt Program
Who cites it
163 citing papers in PubMed, 12 syntheses or guidelines pooled it, 264 citations in OpenAlex.
- Effect of periodontal treatment on adipokines in patients with type 2 diabetes mellitus: A systematic review.Journal of periodontology · 2026Pooled it
- Evidence-based summary and clinical practice suggestions of health education for diabetes mellitus with periodontitis.BMC oral health · 2026Pooled it
- Effects of interprofessional education on dental hygiene students: a systematic review and meta-analysis.BMC medical education · 2025Pooled it
- Efficacy of Adjunctive Local Antimicrobials to Non-Surgical Periodontal Therapy in Pocket Reduction and Glycemic Control of Patients with Type 2 Diabetes: A Network Meta-Analysis.Current diabetes reviews · 2025Pooled it
- Poor glycemic control impairs oral health in children with type 1 diabetes mellitus - a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Periodontitis is associated with the increased levels of visfatin: a meta-analysis.BMC oral health · 2023Pooled it
- Treatment of periodontitis and C-reactive protein: A systematic review and meta-analysis of randomized clinical trials.Journal of clinical periodontology · 2023Pooled it
- The effect of antibiotics on the periodontal treatment of diabetic patients with periodontitis: A systematic review and meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Are Inflamed Periodontal Tissues Endogenous Source of Advanced Glycation End-Products (AGEs) in Individuals with and without Diabetes Mellitus? A Systematic Review.Biomolecules · 2022Pooled it
- Treatment of periodontitis for glycaemic control in people with diabetes mellitus.The Cochrane database of systematic reviews · 2022Pooled it
- Vibrational Spectroscopy Saliva Profiling as Biometric Tool for Disease Diagnostics: A Systematic Literature.Molecules (Basel, Switzerland) · 2020Pooled it
- Periodontitis treatment (surgical and nonsurgical) effects on glycemic control: A review and meta-analysis.Annals of African medicinePooled it
- Non-surgical periodontal therapy with and without hyaluronic acid gel in type 2 diabetic stage-II periodontitis patients: a randomized clinical trial.BMC oral health · 2025Trial
- Community interventions improve diabetes management and oral health in type 2 diabetes patients with chronic periodontitis.Scientific reports · 2025Trial
- Clinical and radiographic evaluation of non-surgical therapy with and without ozone gel application in controlled type 2 diabetic patients with periodontitis: a randomized controlled clinical trial.BMC oral health · 2024Trial
- The Effect of Periodontal Treatment on Clinical and Biological Indicators, Quality of Life, and Oral Health in Rheumatoid Arthritis Patients: A Quasi-Experimental Study.International journal of environmental research and public health · 2022Trial
- Effect of dental intervention on improvements in metabolic syndrome patients: a randomized controlled clinical trial.BMC oral health · 2021Trial
- Endotoxins and Biological Implications-Review.Public health challenges · 2026Review
- Regular dental scaling and dementia risk: a nationwide nested case-control study.BMC oral health · 2026Article
- FAM30A Induces Inflammation and Oxidative Damage in PDLSCs by Targeting miR-424-5p.International dental journal · 2026Article
103 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe evidence is inconclusive regarding the effect of periodontal treatment on glycemic control and systemic inflammation in patients with type 2 diabetes (T2D) and periodontitis. To evaluate the effect of scaling and root planing (SRP) on the metabolic control and systemic inflammation of patients with type 2 diabetes (T2D). METHODOLOGY: A literature search was conducted using the MEDLINE database via PubMed and the Cochrane Central Register of Controlled Trials, from their oldest records up to July 2018. Only randomized clinical trials (RCT) were considered eligible for evaluating the effect of periodontal treatment on markers of metabolic control [glycated hemoglobin (HbA1C)] and systemic inflammation [C-reactive protein (CRP)] in patients with T2D. The quality of the studies was evaluated using the Cochrane Collaboration risk assessment tool. Meta-analyses were performed for HbA1c and CRP using random effects models. The size of the overall intervention effect was estimated by calculating the weighted average of the differences in means (DM) between the groups in each study. Heterogeneity was assessed using the Q-statistic method (x2 and I²). The level of significance was established at p<0.05.
resultsNine RCT were included. SRP was effective in reducing HbA1c [DM=0.56 (0.36-0.75); p<0.01] and CRP [DM=1.89 (1.70-2.08); p<0.01]. No heterogeneity was detected (I2=0%, p>0.05).
conclusionsSRP has an impact on metabolic control and reduction of systemic inflammation of patients with T2D.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.