Evidence map›Paper›PMID 31947529›Full record

Trial reportNutrients2020

Effects of Capsinoids on Daily Physical Activity, Body Composition and Cold Hypersensitivity in Middle-Aged and Older Adults: A Randomized Study.

Keiichi Yokoyama, Yosuke Yamada, Yasunori Akamatsu, Yasuko Yoshinaka, Akiko Yamamoto, Tomonori Koizumi, Kana Ohyama, Katsuya Suzuki, Masaki Hashimoto, Hitoshi Sato and 1 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Frailty Risk Prediction Model among Older Adults: A Chinese Nation-Wide Cross-Sectional Study.International journal of environmental research and public health · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Keiichi YokoyamaInstitute for Active Health, Institutes of Interdisciplinary Research, Kyoto University of Advanced Science, 1-1 Nanjo Otani, Sogabe-cho, Kameoka-city, Kyoto 621-8555, Japan.
Yosuke YamadaInstitute for Active Health, Institutes of Interdisciplinary Research, Kyoto University of Advanced Science, 1-1 Nanjo Otani, Sogabe-cho, Kameoka-city, Kyoto 621-8555, Japan.ORCID 0000-0002-4284-6317
Yasunori AkamatsuCenter for Faculty Development, Kyoto University of Advanced Science, 1-1 Nanjo Otani, Sogabe-cho, Kameoka-city, Kyoto 621-8555, Japan.
Yasuko YoshinakaNonprofit Organization Genki-up AGE Project, Kameoka-city, Kyoto 621-8555, Japan.ORCID 0000-0001-6524-1954
Akiko YamamotoAjinomoto Co., Inc., Institute of Food Sciences & Technologies, 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki City, Kanagawa 210-8681, Japan.
Tomonori KoizumiAjinomoto Co., Inc., Institute of Food Sciences & Technologies, 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki City, Kanagawa 210-8681, Japan.
Kana OhyamaAjinomoto Co., Inc., Task Force for Nutrition Strategy, 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 104-8315, Japan.
Katsuya SuzukiAjinomoto Co., Inc., Institute of Food Sciences & Technologies, 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki City, Kanagawa 210-8681, Japan.
Masaki HashimotoAjinomoto Co., Inc., Direct Marketing Department, 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 104-8315, Japan.
Hitoshi SatoAjinomoto Co., Inc., Quality Assurance Department, 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 104-8315, Japan.
Misaka KimuraInstitute for Active Health, Institutes of Interdisciplinary Research, Kyoto University of Advanced Science, 1-1 Nanjo Otani, Sogabe-cho, Kameoka-city, Kyoto 621-8555, Japan.
Kyoto University of Advanced Science · JPAjinomoto (Japan) · JPSuzuki (Japan) · JPKyoto Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sedentary/inactive lifestyle leads middle-aged and older adults to metabolic syndrome and frailty. Capsinoids from nonpungent chili pepper cultivar have been reported to reduce body fat mass, promote metabolism, and improve unidentified complaints of chills. Additionally, they have an anti-inflammation effect; therefore, we hypothesized that continuous oral ingestion of capsinoids alleviates age-related inflammation in the brain and improves the physical activity (PA) in middle-aged and older adults. In our double-blind human study, 69 participants (17 male, 52 female; mean age: 74.1 ± 7.7 years; range: 52-87 years) were administered either 9 mg of capsinoids which were extracted from pepper fruit variety CH-19 Sweet (

Indexed as

CapsicumAdipose TissueAgedAged, 80 and overAnimalsAnti-Inflammatory AgentsBody CompositionBrainCryopyrin-Associated Periodic SyndromesDouble-Blind MethodEnergy MetabolismExerciseFemaleHumansIntra-Abdominal FatJapanAnti-Inflammatory AgentsPlant Extractsbrain inflammationbrown adipose tissuecapsinoidschilly sensationclinicalenergy expenditureenergy metabolismpercent body fatphysical activityvisceral fat

Identifiers

PMID31947529
PMCPMC7019503
OpenAlexW3000513792

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.