Evidence map›Paper›PMID 31948092›Full record

ReviewBiomolecules2020

Anticancer Potential of Lichens' Secondary Metabolites.

Zuzana Solárová, Alena Liskova, Marek Samec, Peter Kubatka, Dietrich Büsselberg, Peter Solár

Abstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. A New Trichlorinated Xanthone and Compounds Isolated fromPharmaceuticals (Basel, Switzerland) · 2026
    Article
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  7. Natural product as a lead for impairing mitochondrial respiration in cancer cells.Journal of enzyme inhibition and medicinal chemistry · 2025
    Article
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  9. Review
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  13. Review
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zuzana SolárováDepartment of Pharmacology, Faculty of Medicine, P.J. Šafárik University in Košice, 040 01 Košice, Slovakia.
Alena LiskovaDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Marek SamecDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Peter KubatkaDepartment of Medical Biology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Dietrich BüsselbergWeill Cornell Medicine in Qatar, Qatar Foundation-Education City, Doha 24144, Qatar.
Peter SolárDepartment of Medical Biology, Faculty of Medicine, P.J. Šafárik University in Košice, 040 01 Košice, Slovakia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lichens produce different classes of phenolic compounds, including anthraquinones, xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed effective biological activities such as antioxidant, antiviral, antibiotics, antifungal, and anticancer. Although no clinical study has been conducted yet, there are number of in vitro and in vivo studies demonstrating anticancer effects of lichen metabolites. The main goal of our work was to review most recent published papers dealing with anticancer activities of secondary metabolites of lichens and point out to their perspective clinical use in cancer management.

Indexed as

AnimalsAnthraquinonesAntineoplastic AgentsDepsidesDibenzofuransHumansLactonesLichensMolecular StructurePhenolsPlant ExtractsSecondary MetabolismXanthonesAnthraquinonesAntineoplastic AgentsDepsidesdepsidoneDibenzofuransLactonesPhenolsPlant ExtractsXanthonesanticancerin vitroin vivolichensecondary metabolites

Identifiers

PMID31948092
PMCPMC7022966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.