Evidence map›Paper›PMID 31952157›Full record

ReviewJournal of functional biomaterials2020

Fabrication of Polymeric Microparticles by Electrospray: The Impact of Experimental Parameters.

Alan Í S Morais, Ewerton G Vieira, Samson Afewerki, Ricardo B Sousa, Luzia M C Honorio, Anallyne N C O Cambrussi, Jailson A Santos, Roosevelt D S Bezerra, Josy A O Furtini, Edson C Silva-Filho and 2 more

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Review
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  13. Preparation of RDX/F2311/FeMaterials (Basel, Switzerland) · 2024
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alan Í S MoraisLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0002-6974-6455
Ewerton G VieiraLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0002-9537-2995
Samson AfewerkiDivision of Engineering in Medicine, Department of Medicine, Harvard Medical School, Brigham & Women's Hospital, Cambridge, MA 02139, USA.ORCID 0000-0002-5108-6487
Ricardo B SousaFederal Institute of Education, Science and Technology of Tocantins, Dianápolis Campus, IFTO, Dianápolis 77300-000, Tocantins, Brazil.ORCID 0000-0002-5401-039X
Luzia M C HonorioLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.
Anallyne N C O CambrussiLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.
Jailson A SantosLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0001-5102-3999
Roosevelt D S BezerraFederal Institute of Education, Science and Technology of Piauí, Teresina-Central Campus, IFPI, Teresina 64000-040, Brazil.
Josy A O FurtiniLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.
Edson C Silva-FilhoLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0003-0988-2970
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-2028-5969
Anderson O LoboLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0002-2544-0438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microparticles (MPs) with controlled morphologies and sizes have been investigated by several researchers due to their importance in pharmaceutical, ceramic, cosmetic, and food industries to just name a few. In particular, the electrospray (ES) technique has been shown to be a viable alternative for the development of single particles with different dimensions, multiple layers, and varied morphologies. In order to adjust these properties, it is necessary to optimize different experimental parameters, such as polymer solvent, voltage, flow rate (FR), type of collectors, and distance between the collector and needle tip, which will all be highlighted in this review. Moreover, the influence and contributions of each of these parameters on the design and fabrication of polymeric MPs are described. In addition, the most common configurations of ES systems for this purpose are discussed, for instance, the main configuration of an ES system with monoaxial, coaxial, triaxial, and multi-capillary delivery. Finally, the main types of collectors employed, types of synthesized MPs and their applications specifically in the pharmaceutical and biomedical fields will be emphasized. To date, ES is a promising and versatile technology with numerous excellent applications in the pharmaceutical and biomaterials field and such MPs generated should be employed for the improved treatment of cancer, healing of bone, and other persistent medical problems.

Indexed as

biomaterialselectrospraymicroparticlesoperational parameterspolymers

Identifiers

PMID31952157
PMCPMC7151563

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.