Evidence map›Paper›PMID 31952189›Full record

ReviewCells2020

Mitochondrial Quality Control: Role in Cardiac Models of Lethal Ischemia-Reperfusion Injury.

Andrew R Kulek, Anthony Anzell, Joseph M Wider, Thomas H Sanderson, Karin Przyklenk

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
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  17. Mechanistic study of optic atrophy 1 in ischemia-reperfusion disease.Journal of molecular medicine (Berlin, Germany) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrew R KulekCardiovascular Research Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Anthony AnzellCardiovascular Research Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Joseph M WiderDepartments of Emergency Medicine and Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Thomas H SandersonCardiovascular Research Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Karin PrzyklenkCardiovascular Research Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Wayne State University · USUniversity of Michigan · US

Funding

Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain InjuryR42NS105238 · NINDS · MITOVATION, INC. · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2018 to 2020
$1.8M
Detroit Cardiovascular Training ProgramT32HL120822 · NHLBI · WAYNE STATE UNIVERSITY · PI LEVY, PHILLIP DAVID · 2014 to 2023
$1.8M
Limiting brain reperfusion injury by controlling mitochondrial functionR01NS091242 · NINDS · WAYNE STATE UNIVERSITY · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2015 to 2018
$1.3M
NHLBI NIH HHS T32 HL120822NINDS NIH HHS R01 NS091242NINDS NIH HHS R42 NS105238
6 · The paper itself

Abstract

The current standard of care for acute myocardial infarction or 'heart attack' is timely restoration of blood flow to the ischemic region of the heart. While reperfusion is essential for the salvage of ischemic myocardium, re-introduction of blood flow paradoxically

Indexed as

Models, CardiovascularAnimalsBrainHumansMitochondria, HeartMitochondrial DynamicsMyocytes, CardiacReperfusion Injuryfissionfusionheartischemiamitochondriamitophagyreperfusion

Identifiers

PMID31952189
PMCPMC7016592
OpenAlexW3000126426

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.