Evidence mapPaperPMID 31957638Full record

Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2020

Effects of a 12-week yoga versus a 12-week educational film intervention on symptoms of restless legs syndrome and related outcomes: an exploratory randomized controlled trial.

Kim E Innes, Terry Kit Selfe, Caitlin Montgomery, Nicole Hollingshead, Zenzi Huysmans, Roshini Srinivasan, Sijin Wen, Madeleine J Hausmann, Karen Sherman, Maryanna Klatt

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03570515 (Yoga vs. Education for Restless Legs Syndrome - a Feasibility Study), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03570515 nacompletednot on this map

Yoga vs. Education for Restless Legs Syndrome - a Feasibility Study

TypeinterventionalSponsorWest Virginia UniversityRan2015 to 2021Enrolled41ConditionsRestless Legs SyndromeArmsYoga, Educational film
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Unfolding the role of exercise in the management of sleep disorders.European journal of applied physiology · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Sleep disorders and exercise: a mini-review.Journal of thoracic disease · 2023
    Review
  10. Review
  11. Circadian rhythm in restless legs syndrome.Frontiers in neurology · 2023
    Review
  12. Article
  13. Restless Legs Syndrome: Contemporary Diagnosis and Treatment.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  14. Yoga versus educational film intervention in restless legs syndrome: extension of trial may be beneficial to patients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Kim E InnesDepartment of Epidemiology, West Virginia University School of Public Health, Morgantown, West Virginia.
Terry Kit SelfeHealth Science Center Libraries, University of Florida, Gainesville, Florida.
Caitlin MontgomeryDepartment of Epidemiology, West Virginia University School of Public Health, Morgantown, West Virginia.
Nicole HollingsheadDepartment of Family Medicine, The Ohio State University College of Medicine, Columbus, Ohio.
Zenzi HuysmansWest Virginia University College of Physical Activity and Sport Sciences, Morgantown, West Virginia.
Roshini SrinivasanDepartment of Family Medicine, The Ohio State University College of Medicine, Columbus, Ohio.
Sijin WenDepartment of Biostatistics, West Virginia University School of Public Health, Morgantown, West Virginia.
Madeleine J HausmannDepartment of Family Medicine, The Ohio State University College of Medicine, Columbus, Ohio.
Karen ShermanKaiser Permanente Washington Health Research Institute, Seattle, Washington.
Maryanna KlattDepartment of Family Medicine, The Ohio State University College of Medicine, Columbus, Ohio.
The Ohio State University · USWest Virginia University · USKaiser Permanente Washington Health Research Institute · USUniversity of Florida Health Science Center · US

Funding

West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve HealthU54GM104942 · WEST VIRGINIA UNIVERSITY · 2025 to 2025
$4.0M
NCCIH NIH HHS R15 AT008606NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

STUDY

objectivesTo assess the effects of a yoga versus educational film (EF) program on restless legs syndrome (RLS) symptoms and related outcomes in adults with RLS.

methodsForty-one community-dwelling, ambulatory nonpregnant adults with moderate to severe RLS were randomized to a 12-week yoga (n = 19) or EF program (n = 22). In addition to attending classes, all participants completed practice/treatment logs. Yoga group participants were asked to practice at home 30 minutes per day on nonclass days; EF participants were instructed to record any RLS treatments used on their daily logs. Core outcomes assessed pretreatment and posttreatment were RLS symptoms and symptom severity (International RLS Study Group Scale (IRLS) and RLS ordinal scale), sleep quality, mood, perceived stress, and quality of life (QOL).

resultsThirty adults (13 yoga, 17 EF), aged 24 to 73 (mean = 50.4 ± 2.4 years), completed the 12-week study (78% female, 80.5% white). Post-intervention, both groups showed significant improvement in RLS symptoms and severity, perceived stress, mood, and QOL-mental health (P ≤ .04). Relative to the EF group, yoga participants demonstrated significantly greater reductions in RLS symptoms and symptom severity (P ≤ .01), and greater improvements in perceived stress and mood (P ≤ .04), as well as sleep quality (P = .09); RLS symptoms decreased to minimal/mild in 77% of yoga group participants, with none scoring in the severe range by week 12, versus 24% and 12%, respectively, in EF participants. In the yoga group, IRLS and RLS severity scores declined with increasing minutes of homework practice (r = .7, P = .009 and r = .6, P = .03, respectively), suggesting a possible dose-response relationship.

conclusionsFindings of this exploratory RCT suggest that yoga may be effective in reducing RLS symptoms and symptom severity, decreasing perceived stress, and improving mood and sleep in adults with RLS. CLINICAL

trial registrationRegistry: Clinicaltrials.gov; Title: Yoga vs. Education for Restless Legs: a Feasibility Study; Identifier: NCT03570515; URL: https://clinicaltrials.gov/ct2/show/NCT03570515.

Indexed as

Restless Legs SyndromeYogaAdultFeasibility StudiesFemaleHumansMaleQuality of LifeSeverity of Illness IndexSleepeducationexercise therapymental healthmind-bodyquality of liferestless legs syndromesleep disordersyoga

Identifiers

PMID31957638
PMCPMC7053002
OpenAlexW3000624286

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.