ArticleNeurogastroenterology and motility2020
Clinical features and disturbances of gastrointestinal transit in patients with rapid gastric emptying.
Article in Neurogastroenterology and motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Effects of ondansetron on symptoms during a gastric emptying study and enteral lipid challenge and on daily symptoms in diabetic gastroenteropathy.Neurogastroenterology and motility · 2024Trial
- Rapid Gastric Emptying: Insights from a Large Cohort Study on a Controversial Disorder.Digestive diseases and sciences · 2026Article
- Dumping Syndrome After Bariatric Surgery: Advanced Nutritional Perspectives and Integrated Pharmacological Management.Nutrients · 2025Review
- Clinical Relevance of Gastric Emptying Time in Functional Dyspepsia.Journal of neurogastroenterology and motility · 2025Article
- Utility of aNeurogastroenterology and motility · 2025Article
- Inuit population have shorter gastric emptying, higher duodenal motility and altered pan-enteric micromilieu: a comparative study between Greenlandic and Danish populations with and without type 2 diabetes.International journal of circumpolar health · 2024Article
- Gastroparesis might not be uncommon in patients with diabetes mellitus in a real-world clinical setting: a cohort study.BMC gastroenterology · 2024Article
- Gastroparesis and Functional Dyspepsia: Spectrum of Gastroduodenal Neuromuscular Disorders or Unique Entities?Gastro hep advances · 2023Article
- Normal and disordered gastric emptying in diabetes: recent insights into (patho)physiology, management and impact on glycaemic control.Diabetologia · 2022Review
- Epigenetic Alterations Are Associated With Gastric Emptying Disturbances in Diabetes Mellitus.Clinical and translational gastroenterology · 2020Observational
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
aimsSome patients with upper gastrointestinal symptoms have rapid gastric emptying (GE). We aimed to compare patients with normal and rapid GE and to identify phenotypes among patients with rapid GE.
methodsAmong 2798 patients who underwent GE scintigraphy, we compared patients with normal and rapid GE and separately, patients with rapid GE at 1 hour (GE1), 2 hours (GE2), or both (GE12).
resultsIn 2798 patients, GE was normal (74%), delayed (18%), or rapid (8%). Among 211 patients with rapid GE, patterns were rapid GE1 (48%), 2 hours (17%), or 1 and 2 hours (35%); 42 (20%) had diseases that explain rapid GE. A combination of upper and lower gastrointestinal symptoms (54%) was more common that isolated upper (17%) or lower (28%) gastrointestinal symptoms (P < .001). Constipation was more prevalent in patients with rapid GE 2 (72%) than rapid GE 1 (47%) or rapid GE12 hours (67%) (P < .05). Among 179 diabetes mellitus (DM) patients, 15% had rapid GE, which was not associated with the DM phenotype. By multivariable analysis, insulin therapy (odds ratio [OR], 0.36; 95% confidence interval [CI], 0.15-0.88), and weight loss (OR, 0.10; 95% CI, 0.01-0.78) were associated with a lower risk of rapid than normal GE in DM.
conclusionsEight percent of patients undergoing scintigraphy had rapid GE, which is most frequently associated with upper and lower gastrointestinal symptoms; constipation is common. Insulin therapy and weight loss were associated with a lower risk of rapid than normal GE in DM patients.
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