Hormonal and Molecular Regulation of Phallus Differentiation in a Marsupial Tammar Wallaby.

Yu Chen, Marilyn B Renfree

Open access · goldAbstract readReview

In one paragraph

Review in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 99% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Morphological, Histochemical and Immunohistochemical Characterisation of the Penis in Free-Ranging Giant Anteaters (Myrmecophaga tridactyla).Anatomia, histologia, embryologia · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Yu ChenDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32603, USA.

Marilyn B RenfreeSchool of BioSciences, The University of Melbourne, Victoria 3010, Australia.

The University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital anomalies in phalluses caused by endocrine disruptors have gained a great deal of attention due to its annual increasing rate in males. However, the endocrine-driven molecular regulatory mechanism of abnormal phallus development is complex and remains largely unknown. Here, we review the direct effect of androgen and oestrogen on molecular regulation in phalluses using the marsupial tammar wallaby, whose phallus differentiation occurs after birth. We summarize and discuss the molecular mechanisms underlying phallus differentiation mediated by sonic hedgehog (

Indexed as

AndrogensAnimalsCell DifferentiationEndocrine DisruptorsEstrogensFemaleGenitalia, FemaleGenitalia, MaleHedgehog ProteinsInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IMacropodidaeMalePenisReceptors, AndrogenSex DifferentiationAndrogensEndocrine DisruptorsEstrogensHedgehog ProteinsInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IReceptors, AndrogenandrostanediolcastrationIGF1lncRNAmarsupialoestrogenphallusRNAseqSHHWGCNA

Identifiers

PMID31963388

DOI10.3390/genes11010106

PMCPMC7017150

OpenAlexW2999289394

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.