Evidence map›Paper›PMID 31967088›Full record

ArticleJournal of preventive medicine and hygiene2019

Estimates of the incidence of infection-related cancers in Italy and Italian regions in 2018.

S DE Flora, S LA Maestra, E Crocetti, L Mangone, F Bianconi, F Stracci, C Buzzoni

Open access · greenAbstract read
In one paragraph

Article in Journal of preventive medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Estimates of Cancer Mortality Attributable to Carcinogenic Infections in Italy.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

S DE FloraDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
S LA MaestraDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
E CrocettiRomagna Cancer Registry, Romagna Cancer Institute (Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, IRST, IRCCS), Meldola, Forlì, Italy.
L MangoneEpidemiology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
F BianconiIndependent Researcher, Perugia, Italy.
F StracciDepartment of Experimental Medicine, Section of Public Health, University of Perugia, Perugia, Italy.
C BuzzoniClinical Epidemiology Unit, Oncological Network, Prevention and Research Institute (ISPRO), Florence, Italy.
University of Genoa · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic infections and infestations represent one of the leading causes of cancer. Eleven agents have been categorized by the International Agency for Research on Cancer (IARC) in Group 1, 3 in Group 2A and 4 in Group 2B. We previously estimated that the incidence of cancers associated with infectious agents accounted for the 8.5% of new cancer cases diagnosed in Italy in 2014.

methodsIn the present study we evaluated the incidence of cancer in Italy and in the 20 Italian regions in 2018, based on the data of Cancer Registries, and calculated the fraction attributable to infectious agents.

resultsCancers of infectious origin contributed to the overall burden of cancer in Italy with more than 27,000 yearly cases, the 92% of which was attributable to Helicobacter pylori, human papillomaviruses, and hepatitis B and C viruses. With the exception of papillomavirus-related cancers, the incidence of cancers of infectious origin was higher in males (16,000 cases) than in females (11,000 cases). There were regional and geographical variations of cancers depending on the type of cancer and on the gender. Nevertheless, the overall figures were rather similar, the infection-related cancers accounting for the 7.2, 7.6, and 7.1% of all cancers in Northern, Central, and Southern Italy, respectively.

conclusionsThe estimate of the incidence of cancers attributable to infectious agents in Italy in 2018 (7.3% of all cancer cases) is approximately half of the worldwide burden, which has been estimated by IARC to be the 15.4% of all cancer cases in 2012.

Indexed as

AdolescentAdultAgedAge DistributionBurkitt LymphomaCarcinoma, HepatocellularChildChild, PreschoolEpstein-Barr Virus InfectionsFemaleHead and Neck NeoplasmsHelicobacter InfectionsHelicobacter pyloriHepatitis BHepatitis CHodgkin DiseaseCancer incidenceChronic infections and cancerInfection-related cancersItalyRegional distribution

Identifiers

PMID31967088
PMCPMC6953451
OpenAlexW3005569109

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.