Evidence map›Paper›PMID 31967946›Full record

ArticleMolecular biology of the cell2020

Abl signaling directs growth of a pioneer axon in

Akanni Clarke, Philip G McQueen, Hsiao Yu Fang, Ramakrishnan Kannan, Victor Wang, Evan McCreedy, Stephen Wincovitch, Edward Giniger

Open access · bronzeAbstract read
In one paragraph

Article in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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  12. Dynamic morphogenesis of a pioneer axon inMolecular biology of the cell · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Akanni ClarkeNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Philip G McQueenCenter for Information Technology, National Institutes of Health, Bethesda, MD 20892.
Hsiao Yu FangNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Ramakrishnan KannanNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Victor WangCenter for Information Technology, National Institutes of Health, Bethesda, MD 20892.
Evan McCreedyCenter for Information Technology, National Institutes of Health, Bethesda, MD 20892.
Stephen WincovitchNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
Edward GinigerNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-8340-6158
National Institutes of Health · US

Funding

Mechanisms of axon guidance during developmentZIANS003013 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GINIGER, EDWARD · 2009 to 2025
$17.2M
Mechanisms of axon guidance during developmentZ01NS003013 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI GINIGER, EDWARD · 2005 to 2008
$2.0M
Physical modeling of biological systemsZIACT000276 · CIT · CENTER FOR INFORMATION TECHNOLOGY · PI MCQUEEN, PHILIP · 2013 to 2020
$1.5M
Intramural NIH HHS Z01 NS003013
6 · The paper itself

Abstract

The fundamental problem in axon growth and guidance is understanding how cytoplasmic signaling modulates the cytoskeleton to produce directed growth cone motility. Live imaging of the TSM1 axon of the developing

Indexed as

Signal TransductionActinsAnimalsAxonsDrosophila melanogasterDrosophila ProteinsModels, BiologicalMotionPhenotypeProtein-Tyrosine KinasesStochastic ProcessesWavelet AnalysisAbl protein, DrosophilaActinsDrosophila ProteinsProtein-Tyrosine Kinases

Identifiers

PMID31967946
PMCPMC7185895
OpenAlexW3006549102

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.