Evidence mapPaperPMID 31979025Full record

SynthesisNutrients2020

Health Benefits of Whey or Colostrum Supplementation in Adults ≥35 Years; a Systematic Review.

Merran Blair, Nicole J Kellow, Aimee L Dordevic, Stephanie Evans, Julia Caissutti, Tracy A McCaffrey

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Protein intake and bone health: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Pooled it
  5. Pooled it
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Merran BlairDepartment of Nutrition, Dietetics and Food, Monash University, Level 1 264 Ferntree Gully Road, Melbourne VIC 3168, Australia.
Nicole J KellowDepartment of Nutrition, Dietetics and Food, Monash University, Level 1 264 Ferntree Gully Road, Melbourne VIC 3168, Australia.
Aimee L DordevicDepartment of Nutrition, Dietetics and Food, Monash University, Level 1 264 Ferntree Gully Road, Melbourne VIC 3168, Australia.
Stephanie EvansDepartment of Nutrition, Dietetics and Food, Monash University, Level 1 264 Ferntree Gully Road, Melbourne VIC 3168, Australia.
Julia CaissuttiDepartment of Nutrition, Dietetics and Food, Monash University, Level 1 264 Ferntree Gully Road, Melbourne VIC 3168, Australia.
Tracy A McCaffreyDepartment of Nutrition, Dietetics and Food, Monash University, Level 1 264 Ferntree Gully Road, Melbourne VIC 3168, Australia.

Funding

Innovations Connections, Australian Government ICG000673
6 · The paper itself

Abstract

Food-health claims are an important method of translating nutrition research to consumers. Whey and colostrum are thought to exert health benefits to adults, but it is unclear what measurable, objective health benefits they impart. This review aimed to identify the objective health benefits of bovine whey or colostrum-based beverages to healthy adults aged ≥35 years to substantiate a food-health claim. Seven databases were systematically searched. Eligible articles were RCTs that involved healthy adults aged ≥35 years, consuming whey or colostrum in beverage form and measuring objective health markers. Quality assessment and data extraction was conducted in duplicate. The searches identified 9943 papers and 16 were included in this review; 13 studies, reported across 15 papers, related to whey, one study to colostrum. The outcomes identified were body composition, bone mineral density, biochemical markers, such as blood glucose and lipids, and muscle strength and synthesis. Heterogeneous outcomes, high risk of bias and inconsistent findings resulted in inconclusive evidence to substantiate a food-health claim. Clearer reporting and consensus on a minimum set of objective measures would allow for more robust recommendations regarding food-health claims. Protecting consumers from misleading health claims will require collaboration between regulators, researchers, and the food industry.

Indexed as

ColostrumDietary SupplementsAdultAnimalsBlood GlucoseBody CompositionBone DensityCattleDiet, HealthyFemaleHumansMaleMuscle StrengthWheyBlood Glucoseadultsbovine colostrumfood industryhealth claimswhey

Identifiers

PMID31979025
PMCPMC7070284

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.