ArticleHypertension research : official journal of the Japanese Society of Hypertension2020
Association of risk factors for atherosclerosis, including high-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Carotid Plaque Characteristics Combined With Serum Inflammatory Biomarkers Predict Recurrent Ischemic Stroke.Brain and behavior · 2025Article
- Association Between High-Sensitivity C-Reactive Protein and Longitudinal Changes in Arteriosclerosis Over Time: The Kailuan Prospective Cohort Study.Journal of inflammation research · 2025Article
- The Association Between High-Sensitivity C-Reactive Protein and the Progression of Arteriosclerosis: The Kailuan Study.Journal of inflammation research · 2025Article
- Atherosclerosis and arteriosclerosis.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Elevated hs-CRP and Symptomatic Intracranial/Extracranial Artery Stenosis Predict Stroke Recurrence after Acute Ischemic Stroke or TIA.Journal of atherosclerosis and thrombosis · 2023Article
- Insufficient blood pressure control is independently associated with increased arterial stiffness.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- The monomeric C-reactive protein level is associated with the increase in carotid plaque number in patients with subclinical carotid atherosclerosis.Frontiers in cardiovascular medicine · 2022Article
- Associations between measurements of central blood pressure and target organ damage in high-risk patients.Clinical hypertension · 2021Article
- Serum Angiopoietin-like Protein 3 Level Is Associated with Peripheral Arterial Stiffness in Patients with Coronary Artery Disease.Medicina (Kaunas, Lithuania) · 2021Article
- Carotid Artery Atherosclerotic Profile as a Progression Marker for Cardiovascular Disease.Arquivos brasileiros de cardiologia · 2021Article
- Association of Elevated Levels of Inflammatory Marker High-Sensitivity C-Reactive Protein and Hypertension.Journal of primary care & community healthArticle
- Serum anti‑TSTD2 antibody as a biomarker for atherosclerosis‑induced ischemic stroke and chronic kidney disease.Medicine internationalArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intima-media thickness (IMT), plaque score (PS), and brachial-ankle pulse wave velocity (baPWV) are noninvasive parameters used for the evaluation of atherosclerosis. There have been no reports investigating the associations between IMT, PS, or baPWV and known risk factors for atherosclerosis in the same participants. This study aimed to compare the contributing risk factors among IMT, PS, and baPWV. We enrolled 3128 male participants who underwent health checkups. Carotid ultrasonography was used to measure IMT and PS, and baPWV was measured using an automatic device. We analyzed the association between these parameters and risk factors for atherosclerosis including obesity, smoking, alcohol, high blood pressure (BP), impaired fasting glucose (IFG), dyslipidemia (DL), and high-sensitivity C-reactive protein (hs-CRP). Multivariate logistic regression analysis revealed high IMT (>0.9 mm) to be independently associated with high BP. The presence of atherosclerosis (PS ≥ 1.1 mm) was independently associated with high BP, IFG, and DL. In addition, advanced atherosclerosis (PS ≥ 5.1 mm) showed a significant association with high BP, IFG, DL, log hs-CRP, and smoking. High baPWV (≥1600 cm/s) was significantly correlated with high BP, IFG, and log hs-CRP. IMT, PS, and baPWV were all associated with different risk factors among male Japanese participants. Only high BP was a common risk factor for all three parameters. Furthermore, hs-CRP was associated with advanced atherosclerosis but not with the presence of atherosclerosis.
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