Evidence map›Paper›PMID 31988096›Full record

ArticleAntimicrobial agents and chemotherapy2020

Lychnopholide in Poly(d,l-Lactide)-

Renata Tupinambá Branquinho, Carlos Geraldo Campos de Mello, Maykon Tavares Oliveira, Levi Eduardo Soares Reis, Paula Mello de Abreu Vieira, Dênia Antunes Saúde-Guimarães, Vanessa Carla Furtado Mosqueira, Marta de Lana

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Albaconazole Polymeric Nanocapsules for TreatingPathogens (Basel, Switzerland) · 2025
    Article
  4. Plant sesquiterpene lactones.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  5. Review
  6. Nanomedicines against Chagas disease: a critical review.Beilstein journal of nanotechnology · 2024
    Review
  7. Review
  8. Article
  9. ACS omega · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Review on Experimental Treatment Strategies AgainstJournal of experimental pharmacology · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Renata Tupinambá BranquinhoPrograma de Pós-Graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Carlos Geraldo Campos de MelloPrograma de Pós-Graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Maykon Tavares OliveiraPrograma de Pós-Graduação em Ciências Biológicas, Núcleo de Pesquisa em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Levi Eduardo Soares ReisPrograma de Pós-Graduação em Ciências Biológicas, Núcleo de Pesquisa em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Paula Mello de Abreu VieiraPrograma de Pós-Graduação em Ciências Biológicas, Núcleo de Pesquisa em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Dênia Antunes Saúde-GuimarãesPrograma de Pós-Graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Vanessa Carla Furtado MosqueiraPrograma de Pós-Graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Minas Gerais, Brazil.
Marta de LanaPrograma de Pós-Graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Minas Gerais, Brazil delana@nupeb.ufop.br.
Universidade Federal de Ouro Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease remains neglected, and current chemotherapeutics present severe limitations. Lychnopholide (LYC) at low doses loaded in polymeric poly(d,l-lactide)-

Indexed as

AnimalsChagas DiseaseDrug CarriersFemaleLactonesMiceNanocapsulesPolyestersPolyethylene GlycolsSesquiterpenesTrypanocidal AgentsTrypanosoma cruziDrug CarriersLactoneslychnopholidemonomethoxypolyethyleneglycol-polylactide block copolymerNanocapsulesPolyestersPolyethylene Glycolspoly(lactide)SesquiterpenesTrypanocidal Agentsacute phasechronic phaselychnopholidenanocapsulesoral treatmentTrypanosoma cruzi

Identifiers

PMID31988096
PMCPMC7179286
OpenAlexW3004224485

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.