Evidence map›Paper›PMID 31990274›Full record

ArticleeLife2020

Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast.

Courtney R Johnson, Marc G Steingesser, Andrew D Weems, Anum Khan, Amy Gladfelter, Aurélie Bertin, Michael A McMurray

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Chaperone requirements for de novo folding ofMolecular biology of the cell · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. The Structural Biology of Septins and Their Filaments: An Update.Frontiers in cell and developmental biology · 2021
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Courtney R JohnsonDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, United States.
Marc G SteingesserDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, United States.
Andrew D WeemsDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, United States.
Anum KhanDepartment of Biology, University of North Carolina at Chapel Hill, Chapel Hill, United States.
Amy GladfelterDepartment of Biology, University of North Carolina at Chapel Hill, Chapel Hill, United States.
Aurélie BertinLaboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR 168, Paris, France.
Michael A McMurrayDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, United States.ORCID 0000-0002-4615-4334
University of Colorado Anschutz Medical Campus · USUniversity of North Carolina at Chapel Hill · USCentre National de la Recherche Scientifique · FR

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Requirements for cytosolic chaperones in the de novo folding of septin proteinsR01GM124024 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MCMURRAY, MICHAEL A · 2017 to 2021
$1.5M
Mechanisms of assembly and inheritance of yeast septin-containing structuresR00GM086603 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MCMURRAY, MICHAEL A · 2011 to 2013
$711k
Alzheimer's Association NIRGD-12-241119NIGMS NIH HHS P41 GM103311NIGMS NIH HHS R00 GM086603NIGMS NIH HHS R01 GM124024NIGMS NIH HHS R01GM124024
6 · The paper itself

Abstract

Septin proteins evolved from ancestral GTPases and co-assemble into hetero-oligomers and cytoskeletal filaments. In

Indexed as

ArginineBiopolymersGuanidineHot TemperatureSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSeptinsArginineBiopolymersGuanidineSaccharomyces cerevisiae ProteinsSeptinsbiochemistrycell biologychaperonechemical biologyguanidineoligomerizationprotein foldingS. cerevisiaeseptins

Identifiers

PMID31990274
PMCPMC7056273
OpenAlexW3004334777

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.