ArticleRevista da Sociedade Brasileira de Medicina Tropical2020
In vivo antileishmanial activity of Annona mucosa extracts.
Article in Revista da Sociedade Brasileira de Medicina Tropical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors at 2 institutions in 1 country.
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Abstract
introductionLeishmaniasis, a disease caused by a parasite endemic to large areas of tropical and subtropical countries, is a growing public health problem.
methodsMale BALB/c mice were infected with Leishmania amazonensis and treated with extracts isolated from Annona mucosa.
resultsTreated groups had significantly reduced footpad swelling. The group treated intraperitoneally with hexane extract showed footpad swelling similar to groups treated with Pentamidine® and Glucantime®. Groups treated with dichloromethane extract and hexane extract presented the recovering phenotype associated with reduced parasite levels.
conclusionsExtracts of A. mucosa are promising sources of novel antileishmanial compounds.
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