ArticleAmerican journal of respiratory and critical care medicine2020
DNA Methylation Is Predictive of Mortality in Current and Former Smokers.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Recent Evidences of Epigenetic Alterations in Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Circulating DNA-Markers of High Risk for Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease.Bulletin of experimental biology and medicine · 2026Article
- Lung cancer in non-smoking women (LCINSW): from risk factors to precision therapy.Cancer metastasis reviews · 2025Review
- Epigenetic age among US adults with chronic respiratory diseases: results from NHANES 1999-2002.The European respiratory journal · 2025Article
- Role of Epigenetics in Chronic Lung Disease.Cells · 2025Review
- Hub Genes PRPF19 and PPIB: Molecular Pathways and Potential Biomarkers in COPD.International journal of chronic obstructive pulmonary disease · 2025Article
- Clinical promise and applications of epigenetic biomarkers.Clinical epigenetics · 2024Article
- Smoking-Induced DNA Hydroxymethylation Signature Is Less Pronounced than True DNA Methylation: The Population-Based KORA Fit Cohort.Biomolecules · 2024Article
- Peripheral Blood Omics and Other Multiplex-based Systems in Pulmonary and Critical Care Medicine.American journal of respiratory cell and molecular biology · 2023Article
- Epigenome-wide association analysis of infant bronchiolitis severity: a multicenter prospective cohort study.Nature communications · 2023Article
- NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner.Frontiers in immunology · 2023Article
- Hypomethylation ofGenes · 2021Article
- Sex-specific associations with DNA methylation in lung tissue demonstrate smoking interactions.Epigenetics · 2021Article
- Chronological Age Prediction: Developmental Evaluation of DNA Methylation-Based Machine Learning Models.Frontiers in bioengineering and biotechnology · 2021Article
- Multi-Omics Approaches in Immunological Research.Frontiers in immunology · 2021Review
- Epigenome-wide association study on diffusing capacity of the lung.ERJ open research · 2021Article
- Genome-Wide DNA Methylation Profiles in Community Members Exposed to the World Trade Center Disaster.International journal of environmental research and public health · 2020Article
- "PIK"ing Out New Epigenetic Markers in Lung Disease.American journal of respiratory and critical care medicine · 2020Article
Corrections and comments
- Commented on by
Authors and funding
10 authors at 6 institutions in 1 country.
Jarrett D MorrowChanning Division of Network Medicine and.ORCID 0000-0002-5670-5865
Barry MakeNational Jewish Health, Denver, Colorado.
Elizabeth ReganNational Jewish Health, Denver, Colorado.
MeiLan HanDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.
Craig P HershChanning Division of Network Medicine and.ORCID 0000-0002-1342-4334
Ruth Tal-SingerGSK R&D, Collegeville, Pennsylvania.
John QuackenbushDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts; and.
Augustine M K ChoiDepartment of Medicine, NewYork-Presbyterian/Weill Cornell Medical Center, New York, New York.
Edwin K SilvermanChanning Division of Network Medicine and.
Dawn L DeMeoChanning Division of Network Medicine and.ORCID 0000-0001-9653-0636
Brigham and Women's Hospital · USNational Jewish Health · USCornell University · USDana-Farber Cancer Institute · USGlaxoSmithKline (United States) · USUniversity of Michigan · US
Funding
Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9MRespiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9MGenetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7MSystems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2016 to 2020
$12.6MSystems Biology, Bioinformatics, and BiostatisticsP01HL105339 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2011 to 2015
$12.2MUsing Networks to Assign Gene Function in Lung DiseaseR01HL111759 · NHLBI · DANA-FARBER CANCER INST · PI QUACKENBUSH, JOHN, SILVERMAN, EDWIN K · 2012 to 2015
$3.4MImpact of CPAP on Functional Outcomes in Milder OSAR01HL076101 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WEAVER, TERRI ELIZABETH · 2003 to 2006
$2.6MModeling of Lung HIV Cytokine/Chemokine NetworksR01HL076114 · NHLBI · BOSTON MEDICAL CENTER · PI SKOLNIK, PAUL R · 2003 to 2006
$1.8MTraining Program in Academic Pulmonary MedicineT32HL076118 · NHLBI · EMORY UNIVERSITY · PI HART, C MICHAEL · 2004 to 2013
$1.7MNeurotrophins and Development of Baroreceptor Pathways.R01HL076113 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BALKOWIEC, AGNIESZKA Z · 2005 to 2009
$1.5MIntegrative omics pipeline to identify novel COPD genes and pathwaysK25HL136846 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORROW, JARRETT · 2017 to 2021
$945kCLINICAL COORDINATING CENTER FOR LVRS-N01HR76119-268076119-268076119N01HR076119 · HR · JOHNS HOPKINS UNIVERSITY · PI PIANTADOSI, STEVEN · 1997 to 2006
$871kNHLBI NIH HHS K25 HL136846NHLBI NIH HHS N01 HR076101NHLBI NIH HHS N01 HR076102NHLBI NIH HHS N01 HR076103NHLBI NIH HHS N01 HR076104NHLBI NIH HHS N01 HR076105NHLBI NIH HHS N01 HR076106NHLBI NIH HHS N01 HR076107NHLBI NIH HHS N01 HR076108NHLBI NIH HHS N01 HR076109NHLBI NIH HHS N01 HR076110NHLBI NIH HHS N01 HR076111NHLBI NIH HHS N01 HR076112NHLBI NIH HHS N01 HR076113NHLBI NIH HHS N01 HR076114NHLBI NIH HHS N01 HR076115NHLBI NIH HHS N01 HR076116NHLBI NIH HHS N01 HR076118NHLBI NIH HHS N01 HR076119NHLBI NIH HHS P01 HL105339NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL111759NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
Abstract
PubMed holds no abstract for this paper.
Indexed as
DNA MethylationPredictive Value of TestsAdultAgedAged, 80 and overBiomarkers, TumorCohort StudiesEpigenesis, GeneticFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveSmokingBiomarkers, Tumorall-cause mortalitychronic obstructive pulmonary diseaseDNA methylationepigeneticssurvival analysis
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.