Evidence map›Paper›PMID 31998708›Full record

ReviewFrontiers in bioengineering and biotechnology2019

Engineering Tissue Fabrication With Machine Intelligence: Generating a Blueprint for Regeneration.

Joohyun Kim, Jane A McKee, Jake J Fontenot, Jangwook P Jung

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Engineered Tissue Models to Decode Host-Microbiota Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Machine Learning in Tissue Engineering.Tissue engineering. Part A · 2023
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Towards the Experimentally-InformedFrontiers in bioengineering and biotechnology · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joohyun KimCenter for Computation and Technology, Louisiana State University, Baton Rouge, LA, United States.
Jane A McKeeDepartment of Biological Engineering, Louisiana State University, Baton Rouge, LA, United States.
Jake J FontenotDepartment of Biological Engineering, Louisiana State University, Baton Rouge, LA, United States.
Jangwook P JungDepartment of Biological Engineering, Louisiana State University, Baton Rouge, LA, United States.

Funding

STABILITY' (symptomatic review during biologic therapy) Review in Inflammatory Bowel DiseaseP20GM103424 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI VLADIMIR N CHOULJENKO · 2012 to 2026
$57.4M
Protein CoreP30GM110760 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI KOUSOULAS, KONSTANTIN G · 2014 to 2018
$5.6M
NIGMS NIH HHS P20 GM103424NIGMS NIH HHS P30 GM110760
6 · The paper itself

Abstract

Regenerating lost or damaged tissue is the primary goal of Tissue Engineering. 3D bioprinting technologies have been widely applied in many research areas of tissue regeneration and disease modeling with unprecedented spatial resolution and tissue-like complexity. However, the extraction of tissue architecture and the generation of high-resolution blueprints are challenging tasks for tissue regeneration. Traditionally, such spatial information is obtained from a collection of microscopic images and then combined together to visualize regions of interest. To fabricate such engineered tissues, rendered microscopic images are transformed to code to inform a 3D bioprinting process. If this process is augmented with data-driven approaches and streamlined with machine intelligence, identification of an optimal blueprint can become an achievable task for functional tissue regeneration. In this review, our perspective is guided by an emerging paradigm to generate a blueprint for regeneration with machine intelligence. First, we reviewed recent articles with respect to our perspective for machine intelligence-driven information retrieval and fabrication. After briefly introducing recent trends in information retrieval methods from publicly available data, our discussion is focused on recent works that use machine intelligence to discover tissue architectures from imaging and spectral data. Then, our focus is on utilizing optimization approaches to increase print fidelity and enhance biomimicry with machine learning (ML) strategies to acquire a blueprint ready for 3D bioprinting.

Indexed as

bioprintingcardiovascularmachine intelligencemachine learningtissue engineering

Identifiers

PMID31998708
PMCPMC6967031

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.