Evidence map›Paper›PMID 32004990›Full record

ArticleiScience2020

A Role of Histone Acetylation in the Regulation of Circadian Rhythm in Ants.

Romain Libbrecht, Dennis Nadrau, Susanne Foitzik

Open access · goldAbstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A neural mScience China. Life sciences · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Tip60 Phosphorylation at Ser 99 Is Essential for Autophagy Induction inInternational journal of molecular sciences · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Romain LibbrechtInstitute of Organismic and Molecular Evolution (IOME), Johannes Gutenberg University Mainz, Biozentrum I, Hanns Dieter Hüsch Weg 15, 55128 Mainz, Germany. Electronic address: romain.libbrecht@gmail.com.
Dennis NadrauInstitute of Organismic and Molecular Evolution (IOME), Johannes Gutenberg University Mainz, Biozentrum I, Hanns Dieter Hüsch Weg 15, 55128 Mainz, Germany.
Susanne FoitzikInstitute of Organismic and Molecular Evolution (IOME), Johannes Gutenberg University Mainz, Biozentrum I, Hanns Dieter Hüsch Weg 15, 55128 Mainz, Germany.
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In many organisms, circadian rhythms and associated oscillations in gene expression are controlled by post-translational modifications of histone proteins. Although epigenetic mechanisms influence key aspects of insect societies, their implication in regulating circadian rhythms has not been studied in social insects. Here we ask whether histone acetylation plays a role in adjusting circadian activity in the ant Temnothorax longispinosus. We characterized activity patterns in 20 colonies to reveal that these ants exhibit a diurnal rhythm in colony-level activity and can rapidly respond to changes in the light regime. Then we fed T. longispinosus colonies with C646, a chemical inhibitor of histone acetyltransferases, to show that treated colonies lost their circadian rhythmicity and failed to adjust their activity to the light regime. These findings suggest a role for histone acetylation in controlling rhythmicity in ants and implicate epigenetic processes in the regulation of circadian rhythms in a social context.

Indexed as

EntomologyMolecular BiologyMolecular Mechanism of Behavior

Identifiers

PMID32004990
PMCPMC6995257
OpenAlexW2996812219

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.