ArticleJournal of immunology (Baltimore, Md. : 1950)2020
Cooperative Regulation of the Mucosal Mast Cell-Specific Protease Genes
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Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies.European journal of immunology · 2025Review
- PU.1 and TGF-β signaling activate the cell-surface expression of CD103 in mast cells and dendritic cells: opposite roles of GATA2 in the expression of mucosal mast cell genes.The FEBS journal · 2025Article
- Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation.Immunological reviews · 2025Review
- Article
- Transcriptional regulation of basophil-specific protease genes by C/EBPα, GATA2, TGF-β signaling, and epigenetic mechanisms.FEBS letters · 2025Article
- TGF-β1 Induces Mucosal Mast Cell Genes and is Negatively Regulated by the IL-3/ERK1/2 Axis.Cell communication and signaling : CCS · 2025Article
- Basophil-Derived IL-4 and IL-13 Protect Intestinal Barrier Integrity and Control Bacterial Translocation during Malaria.ImmunoHorizons · 2024Article
- IL-10 Modulates the Expression and Activation of Pattern Recognition Receptors in Mast Cells.International journal of molecular sciences · 2023Article
- Kaempferol Suppresses the Activation of Mast Cells by Modulating the Expression of FcεRI and SHIP1.International journal of molecular sciences · 2023Article
- New Mechanistic Advances in FcεRI-Mast Cell-Mediated Allergic Signaling.Clinical reviews in allergy & immunology · 2022Review
- The Role of TGFβ and Other Cytokines in Regulating Mast Cell Functions in Allergic Inflammation.International journal of molecular sciences · 2022Review
- Article
- Basophil Depletion Alters Host Immunity, Intestinal Permeability, and Mammalian Host-to-Mosquito Transmission in Malaria.ImmunoHorizons · 2022Article
- Salicylaldehyde Suppresses IgE-Mediated Activation of Mast Cells and Ameliorates Anaphylaxis in Mice.International journal of molecular sciences · 2022Article
- Review
- IL-10 in Mast Cell-Mediated Immune Responses: Anti-Inflammatory and Proinflammatory Roles.International journal of molecular sciences · 2021Review
- Anaphylaxis: Focus on Transcription Factor Activity.International journal of molecular sciences · 2021Review
- Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation.The Journal of experimental medicine · 2021Article
- Transcription Factors in the Development and Pro-Allergic Function of Mast Cells.Frontiers in allergy · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 2 countries.
Kazumi KasakuraLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.ORCID 0000-0002-4412-3737
Kazuki NagataLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.
Ryosuke MiuraLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.ORCID 0000-0003-1249-7803
Mayu IidaLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.ORCID 0000-0003-2260-502X
Hikaru NakayaLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.
Hikaru OkadaLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.
Takahiro AraiLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.
Takahiro AraiLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.
Yuko KawakamiDivision of Cell Biology, La Jolla Institute for Immunology, La Jolla, CA 92037.
Toshiaki KawakamiDivision of Cell Biology, La Jolla Institute for Immunology, La Jolla, CA 92037.
Takuya YashiroLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and.ORCID 0000-0002-9319-3467
Chiharu NishiyamaLaboratory of Molecular and Cellular Immunology, Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan; and chinishi@rs.tus.ac.jp.ORCID 0000-0002-4082-9097
Tokyo University of Science · JPLa Jolla Institute for Immunology · US
Funding
Histamine-Releasing Factor Oligomers in Food AllergyR01AI146042 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI KAWAKAMI, TOSHIAKI · 2019 to 2022
$2.5MNIAID NIH HHS R01 AI146042
Abstract
Mouse mast cell proteases (mMCP)-1 and -2 are specifically expressed in mucosal mast cells (MCs). However, the transcriptional regulation mechanism of the
Indexed as
AnimalsCells, CulturedChymasesEnhancer Elements, GeneticGATA1 Transcription FactorGATA2 Transcription FactorGene Knockdown TechniquesHEK293 CellsHumansImmunity, MucosalMast CellsMiceMucous MembranePrimary Cell CultureRecombinant ProteinsRNA, Messengerchymase 2ChymasesGata1 protein, mouseGATA1 Transcription FactorGata2 protein, mouseGATA2 Transcription FactorMcpt1 protein, mouseRecombinant ProteinsRNA, MessengerRNA, Small InterferingSmad2 ProteinSmad2 protein, mouseSmad4 ProteinSmad4 protein, mouseTgfb1 protein, mouseTransforming Growth Factor beta1
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.