Evidence mapPaperPMID 32010598Full record

ReviewJournal of translational internal medicine2019

Research Progress in Acute Hypertensive Renal Injury by "

Da Sun, Jiaojiao Wang, Li Yao, Zilong Li, Shinichi Ohno

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of translational internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Da SunDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Jiaojiao WangDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Li YaoDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Zilong LiDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Shinichi OhnoUniversity of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, Japan.
China Medical University · CNFirst Hospital of China Medical University · CNUniversity of Yamanashi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial hypertension has a large prevalence in the general population and as a major hypertensive target organ, the involvement of kidney is usually hard to avoid and gradually develops into chronic kidney disease (CKD). Acute hypertension is defined as a blood pressure greater than 180/120, also known as hypertensive emergency (HE). In acute severe hypertension, the pathophysiology damage to the kidney tends to worsen on the basis of chronic damage, and accounts for more significant mortality. However, the mechanisms of renal injury induced by acute hypertension remain unclear. This review summarizes the clinical and histopathological features of hypertensive renal injury by using "in vivo cyrotechnique" and focusses on the interplay of distinct systemic signaling pathways, which drive glomerular podocyte injury. A thorough understanding of the cellular and molecular mechanisms of kidney damage and repair in hypertension will provide significant insight into the development of new research methods and therapeutic strategies for global CKD progression.

Indexed as

acute hypertensionhypertensive renal injuryin vivo cryotechnique

Identifiers

PMID32010598
PMCPMC6985919
OpenAlexW3001344435

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.