Evidence map›Paper›PMID 32020441›Full record

SynthesisWorld journal of pediatrics : WJP2020

Childhood obesity, cardiovascular and liver health: a growing epidemic with age.

Maria Felicia Faienza, Mariangela Chiarito, Emilio Molina-Molina, Harshitha Shanmugam, Frank Lammert, Marcin Krawczyk, Gabriele D'Amato, Piero Portincasa

2 registry-linked trialsOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in World journal of pediatrics : WJP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05447351 unknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Personalized Dietary and Lifestyle Treatments on the Reduction of Cardiovascular and Metabolic Risk in Overweight and Obese Patients

Typeobservational_patient_registrySponsorUniversity of BariRan2023 to 2025Enrolled200ConditionsOverweight and Obesity, Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
NCT07035704 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

De-Risking Metabolic, Environmental and Behavioral Determinants of Obesity in Children, Adolescents and Young Adults

TypeinterventionalSponsorpiero portincasaRan2025 to 2027Enrolled200ConditionsOverweight (BMI &gt, 25)ArmsMeD enriched with mushrooms, MeD enriched the Lebanese herbal mixture Za'atar, MeD Diet + semaglutinine or compatible treatment+ Za'atar or Mushroom (to be defined)
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 95 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Maria Felicia FaienzaSection of Pediatrics, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Bari, Italy. mariafelicia.faienza@uniba.it.ORCID http://orcid.org/0000-0002-1899-8337
Mariangela ChiaritoSection of Pediatrics, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
Emilio Molina-MolinaClinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
Harshitha ShanmugamClinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
Frank LammertDepartment of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany.
Marcin KrawczykDepartment of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany.
Gabriele D'AmatoNeonatal Intensive Care Unit, Di Venere Hospital, Bari, Italy.
Piero PortincasaClinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
University of Bari Aldo Moro · ITMedical University of Warsaw · PLSaarland University · DE

Funding

722619 Fois Gras
6 · The paper itself

Abstract

backgroundThe frequency of childhood obesity has increased over the last 3 decades, and the trend constitutes a worrisome epidemic worldwide. With the raising obesity risk, key aspects to consider are accurate body mass index classification, as well as metabolic and cardiovascular, and hepatic consequences. DATA SOURCES: The authors performed a systematic literature search in PubMed and EMBASE, using selected key words (obesity, childhood, cardiovascular, liver health). In particular, they focused their search on papers evaluating the impact of obesity on cardiovascular and liver health.

resultsWe evaluated the current literature dealing with the impact of excessive body fat accumulation in childhood and across adulthood, as a predisposing factor to cardiovascular and hepatic alterations. We also evaluated the impact of physical and dietary behaviors starting from childhood on cardio-metabolic consequences.

conclusionsThe epidemic of obesity and obesity-related comorbidities worldwide raises concerns about the impact of early abnormalities during childhood and adolescence. Two key abnormalities in this context include cardiovascular diseases, and nonalcoholic fatty liver disease. Appropriate metabolic screenings and associated comorbidities should start as early as possible in obese children and adolescents. Nevertheless, improving dietary intake and increasing physical activity performance are to date the best therapeutic tools in children to weaken the onset of obesity, cardiovascular diseases, and diabetes risk during adulthood.

Indexed as

Age FactorsCardiovascular DiseasesChildGlobal HealthHumansLiver DiseasesPediatric ObesityCardiovascularChildhoodLiver healthObesity

Identifiers

PMID32020441
PMCPMC7224053
OpenAlexW3004961686

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.