Evidence map›Paper›PMID 32021367›Full record

ArticleClinical, cosmetic and investigational dermatology2020

A

Annalisa Tito, Massimiliano Minale, Salvatore Riccio, Fabrizia Grieco, Maria Gabriella Colucci, Fabio Apone

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Electrospun Fibers EncapsulatingMolecules (Basel, Switzerland) · 2026
    Article
  4. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  5. Evaluation of Biological Effect ofAdvances in pharmacological and pharmaceutical sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Journal of clinical medicine · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. International journal of microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Annalisa TitoArterra Bioscience Srl, Naples, 80142, Italy.ORCID 0000-0002-6017-1253
Massimiliano MinaleFarmaceutici Damor S.p.A., Naples 80145, Italy.
Salvatore RiccioFarmaceutici Damor S.p.A., Naples 80145, Italy.ORCID 0000-0003-2658-0632
Fabrizia GriecoFarmaceutici Damor S.p.A., Naples 80145, Italy.ORCID 0000-0001-5381-1470
Maria Gabriella ColucciArterra Bioscience Srl, Naples, 80142, Italy.
Fabio AponeArterra Bioscience Srl, Naples, 80142, Italy.
Farmaceutici Damor (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic skin lesions represent a problem of increasing occurrence, mostly due to the global ageing of the world population. Research in skin care and dermatology is constantly looking for new non-invasive solutions, preferably those based on the use of natural certified products, able to accelerate the spontaneous skin repair mechanisms and without altering the skin normal appearance and functionality. The wound healing process in the skin is finely regulated by several factors and orchestrated mechanisms, which modulate the progression and the fitting of different consequent phases, including haemostasis, inflammation, cell proliferation and tissue remodelling. It was previously shown that a patented

methodsScratch assay was performed in Human Dermal Fibroblasts (HDF). The production of fibronectin was measured by gene expression, protein quantification and localization using specific antibodies in HDF. The polymerization of actin was measured using rhodamin-phalloidin in HDF. The epidermal lipid content was estimated in HaCaT (human spontaneously immortalized keratinocytes) using Nile Red staining and the increasing GBA gene expression and activity was demonstrated by RT-PCR and enzymatic activity assay.

resultsIn the present study, it was demonstrated that the

conclusionIn conclusion, we demonstrated that the

Indexed as

ECM componentepidermal barrierplant extractskin cell culturewound healing

Identifiers

PMID32021367
PMCPMC6969697
OpenAlexW2999870630

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.