Evidence map›Paper›PMID 32024695›Full record

ArticleThe Journal of biological chemistry2020

The glutamic acid-rich-long C-terminal extension of troponin T has a critical role in insect muscle functions.

Tianxin Cao, Alyson Sujkowski, Tyler Cobb, Robert J Wessells, Jian-Ping Jin

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Identification and Characterization ofInternational journal of molecular sciences · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. CytochromeCells · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tianxin CaoDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201.
Alyson SujkowskiDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201.ORCID 0000-0002-9909-9279
Tyler CobbDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201.
Robert J WessellsDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201.
Jian-Ping JinDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201 jjin@med.wayne.edu.
Wayne State University · US

Funding

Regulation of Troponin I in Cardiac Adaptation & FailureR01HL127691 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2016 to 2026
$3.5M
Octpamine controls adaptation to endurance exercise in DrosophilaR01AG059683 · NIA · WAYNE STATE UNIVERSITY · PI Robert John Wessells · 2018 to 2026
$3.0M
Targeting Troponin T Regulation to Sustain Cardiac Function in Heart FailureR01HL138007 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2018 to 2026
$2.4M
NHLBI NIH HHS R01 HL127691NHLBI NIH HHS R01 HL138007NIA NIH HHS R01 AG059683
6 · The paper itself

Abstract

The troponin complex regulates the Ca

Indexed as

Alternative SplicingAnimalsCalciumCD27 LigandDrosophilaDrosophila ProteinsFemaleFlight, AnimalGlutamic AcidMaleMuscle ContractionMuscle, SkeletalMutagenesisMyofibrilsPhylogenyProtein DomainsCalciumCD27 LigandDrosophila ProteinsGlutamic AcidRecombinant ProteinsTropomyosinTroponin Tcalcium homeostasiscontractile proteinDrosophilainvertebratemolecular evolutionmuscle physiologystriated muscleTnTtropomyosintroponin

Identifiers

PMID32024695
PMCPMC7086023
OpenAlexW3005057220

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.