Evidence map›Paper›PMID 32026128›Full record

ArticleJournal of medical ultrasonics (2001)2020

Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells.

Yoshiaki Tabuchi, Hideyuki Hasegawa, Nobuo Suzuki, Yukihiro Furusawa, Tetsushi Hirano, Ryo Nagaoka, Shin-Ichi Takeuchi, Michihisa Shiiba, Takashi Mochizuki

Abstract read
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In one paragraph

Article in Journal of medical ultrasonics (2001), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yoshiaki TabuchiDivision of Molecular Genetics Research, Life Science Research Center, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan. ytabu@cts.u-toyama.ac.jp.ORCID http://orcid.org/0000-0002-6007-6176
Hideyuki HasegawaGraduate School of Science and Engineering, University of Toyama, Toyama, Japan.
Nobuo SuzukiNoto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University, Ishikawa, Japan.
Yukihiro FurusawaDepartment of Liberal Arts and Sciences, Toyama Prefectural University, Toyama, Japan.
Tetsushi HiranoDivision of Molecular Genetics Research, Life Science Research Center, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
Ryo NagaokaGraduate School of Science and Engineering, University of Toyama, Toyama, Japan.
Shin-Ichi TakeuchiGraduate School of Biomedical Engineering, Toin University of Yokohama, Yokohama, Japan.
Michihisa ShiibaFaculty of Health Sciences, Nihon Institute of Medical Science, Saitama, Japan.
Takashi MochizukiMedical Ultrasound Laboratory, Co., Ltd., Tokyo, Japan.
University of Toyama · JPKanazawa University · JPNihon Institute of Medical Science · JPToin University of Yokohama · JPToyama Prefectural University · JP

Funding

Japan Society for the Promotion of Science JP17K01353Japan Society for the Promotion of Science JP26560205
6 · The paper itself

Abstract

purposeThe effects of low-intensity pulsed ultrasound (LIPUS) on the expression of immediate-early genes (IEGs) in bone marrow stromal cells (BMSCs) were evaluated to elucidate the early cellular response to LIPUS.

methodsMouse ST2 BMSCs were treated with LIPUS (I

resultsA single exposure of LIPUS at an intensity of 25 mW/cm

conclusionThese results suggest that LIPUS exposure significantly induces expression of IEGs such as Fos and Egr1 via the MAPK/ERK pathway in ST2 BMSCs.

Indexed as

Ultrasonic WavesAnimalsCell DifferentiationCell ProliferationCells, CulturedGene ExpressionGenes, Immediate-EarlyInterleukin-1 Receptor-Like 1 ProteinMesenchymal Stem CellsMiceIl1rl1 protein, mouseInterleukin-1 Receptor-Like 1 ProteinGene expressionImmediate-early genesLow-intensity pulsed ultrasoundMAPK/ERK pathwayST2 bone marrow stromal cell

Identifiers

PMID32026128
OpenAlexW3005070731

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.