Evidence map›Paper›PMID 32028652›Full record

ArticleJournal of clinical medicine2020

Circulating Arsenic is Associated with Long-Term Risk of Graft Failure in Kidney Transplant Recipients: A Prospective Cohort Study.

Camilo G Sotomayor, Dion Groothof, Joppe J Vodegel, Tomás A Gacitúa, António W Gomes-Neto, Maryse C J Osté, Robert A Pol, Catterina Ferreccio, Stefan P Berger, Guillermo Chong and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Plasma Vitamin BNutrients · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Camilo G SotomayorDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-6835-6386
Dion GroothofDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Joppe J VodegelDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-2115-5883
Tomás A GacitúaDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-8833-5352
António W Gomes-NetoDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-4398-4877
Maryse C J OstéDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-9238-1397
Robert A PolDivision of Transplantation Surgery, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Catterina FerreccioAdvanced Center for Chronic Diseases, Pontificia Universidad Católica de Chile, 8330033 Santiago, Chile.
Stefan P BergerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Guillermo ChongDepartment of Radiology, Clínica Alemana de Santiago, Universidad del Desarrollo, 7610658 Santiago, Chile.
Riemer H J A SlartDepartment of Nuclear and Molecular Imaging, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Ramón RodrigoInstitute of Biomedical Sciences, Faculty of Medicine, University of Chile, CP 8380453 Santiago, Chile.ORCID 0000-0003-1724-571X
Gerjan J NavisDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Daan J TouwDepartment of Pharmacy and Clinical Pharmacology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Stephan J L BakkerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0003-3356-6791
University Medical Center Groningen · NLPontificia Universidad Católica de Chile · CLUniversidad del Desarrollo · CLUniversity of Chile · CL

Funding

CONICYT F72190118Top Institute Food and Nutrition of the Netherlands grant A-1003
6 · The paper itself

Abstract

Arsenic is toxic to many organ systems, the kidney being the most sensitive target organ. We aimed to investigate whether, in kidney transplant recipients (KTRs), the nephrotoxic exposure to arsenic could represent an overlooked hazard for graft survival. We performed a prospective cohort study of 665 KTRs with a functional graft ≥1 year, recruited in a university setting (2008‒2011), in The Netherlands. Plasma arsenic was measured by ICP-MS, and dietary intake was comprehensively assessed using a validated 177-item food-frequency questionnaire. The endpoint graft failure was defined as restart of dialysis or re-transplantation. Median arsenic concentration was 1.26 (IQR, 1.04‒2.04) µg/L. In backwards linear regression analyses we found that fish consumption (std β = 0.26;

Indexed as

arsenicdietfish consumptiongraft failurekidney transplantationoxidative stress

Identifiers

PMID32028652
PMCPMC7073559
OpenAlexW3004137890

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.