Evidence map›Paper›PMID 32034085›Full record

ArticleImmunoHorizons2020

CD8

Hyoung-Soo Cho, Soyoung Ha, Hyun Mu Shin, Andrea Reboldi, Jason A Hall, Jun R Huh, Edward J Usherwood, Leslie J Berg

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Interferon regulatory factors orchestrate CD8International journal of molecular medicine · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Dysregulation of CD4Journal for immunotherapy of cancer · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. TCR Signal Strength and Antigen Affinity Regulate CD8Journal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Hyoung-Soo ChoDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.ORCID 0000-0003-0899-8541
Soyoung HaDepartment of Immunology, Harvard Medical School, Boston, MA 02115.
Hyun Mu ShinDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.ORCID 0000-0002-4521-8391
Andrea ReboldiDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Jason A HallThe Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016; and.
Jun R HuhDepartment of Immunology, Harvard Medical School, Boston, MA 02115.
Edward J UsherwoodDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.ORCID 0000-0002-5611-9700
Leslie J BergDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605; leslie.berg@cuanschutz.edu.
University of Massachusetts Chan Medical School · USHarvard University · USDartmouth College · USNew York University · US

Funding

University of Colorado Anschutz Medical Campus DRCP30DK116073 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI LORI SUSSEL · 2020 to 2026
$10.8M
Tec family tyrosine kinases in T cell signalingR01AI037584 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BERG, LESLIE JOAN · 1995 to 2009
$2.8M
Dissecting the pathways controlling tunable responses to TCR signalingR01AI132419 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BERG, LESLIE JOAN · 2018 to 2022
$2.5M
NIAID NIH HHS R01 AI037584NIAID NIH HHS R01 AI132419NIDDK NIH HHS P30 DK116073
6 · The paper itself

Abstract

The Tec kinase IL-2-inducible T cell kinase (ITK) regulates the expression of TCR-induced genes.

Indexed as

Chemotaxis, LeukocyteSignal TransductionAdoptive TransferAnimalsCD8-Positive T-LymphocytesCells, CulturedInterferon Regulatory Factor-4Interferon Regulatory FactorsIntestinesMiceMice, Inbred C57BLMice, KnockoutProtein-Tyrosine KinasesReceptors, Lymphocyte HomingRhadinovirusVirus Replicationemt protein-tyrosine kinaseInterferon Regulatory Factor-4Interferon Regulatory FactorsProtein-Tyrosine KinasesReceptors, Lymphocyte Homing

Identifiers

PMID32034085
PMCPMC7521019
OpenAlexW3004813232

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.