ArticleRespiratory research2020
The impact on incident tuberculosis by kidney function impairment status: analysis of severity relationship.
Article in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk of Tuberculosis Disease in People With Chronic Kidney Disease Without Kidney Failure: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Pooled it
- Multidrug resistant tuberculosis (MDR-TB) in Eritrea: a retrospective cohort analysis of mortality and associated factors (2013 - 2023).Frontiers in cellular and infection microbiology · 2026Article
- Clinical presentation and outcome of tuberculosis in chronic kidney disease stage 4 & 5 from a high TB burden country.PloS one · 2025Article
- Significant association between methyl mercury level and latent tuberculosis infection risk: a cross-sectional study.BMC pulmonary medicine · 2024Article
- Clinical epidemiological and laboratory investigation in co-infection with COVID-19 and tuberculosis.Revista do Instituto de Medicina Tropical de Sao Paulo · 2024Article
- Article
- Assessment of the Association of Vitamin D and the Risk of Tuberculosis among End-Stage Kidney Disease Population.Life (Basel, Switzerland) · 2022Article
- Update of the mechanism and characteristics of tuberculosis in chronic kidney disease : Review article.Wiener klinische Wochenschrift · 2022Review
- Reliable Sarcoidosis Detection Using Chest X-rays with EfficientNets and Stain-Normalization Techniques.Sensors (Basel, Switzerland) · 2022Article
- Effect of chronic kidney disease on all-cause mortality in tuberculosis disease: an Australian cohort study.BMC infectious diseases · 2022Article
- A study of risk factors for tuberculous meningitis among patients with tuberculosis in China: An analysis of data between 2012 and 2019.Frontiers in public health · 2022Article
- Clinical Characteristics and Outcomes in Chronic Kidney Disease Patients with Tuberculosis in China: A Retrospective Cohort Study.International journal of general medicine · 2022Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risk of tuberculosis (TB) in patients with impaired kidney function remains unclear by different stages of renal function impairment.
methodsWe retrospectively recruited all patients with kidney function in a tertiary-care referral center from January 2008 to December 2013 and followed them till December 2016. We defined the primary outcome as active TB development and analyzed the impact of kidney function impairment.
resultsDuring the study period, a total of 289,579 patients were enrolled for analysis, and of them, 1012 patients had active TB events in an average of 4.13 years of follow-up. According to kidney function impairment, the incidence rate of TB was similar in patients with no chronic kidney disease (CKD) or stage 1 and stage 2, and it increased apparently at stage 3a (167.68 per 100,000 person-years) to stage 3b, stage 4 and stage 5 (229.25, 304.95 and 349.29 per 100,000 person-years, respectively). In a Cox proportional hazard regression model, the dose response of TB risk among different stages of kidney function impairment increased significantly from CKD stage 3a to stage 5. Patients with long-term dialysis had a hazard ratio of 2.041 (1.092-3.815, p = 0.0254), which is similar to that of stage 4 CKD but lower than that of stage 5.
conclusionIn patients with impaired kidney function, the risk of TB increases from CKD stage 3, and in stage 5, the risk is even higher than that of those receiving dialysis. Further strategies of TB control need to consider this high-risk group.
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