ReviewSeminars in immunopathology2020
Recent findings in the genetics and epigenetics of asthma and allergy.
Review in Seminars in immunopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases.Frontiers in immunology · 2023Pooled it
- Are prenatal anxiety or depression symptoms associated with asthma or atopic diseases throughout the offspring's childhood? An updated systematic review and meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Folic Acid Level of Children with Atopy/Asthma and Children Without Chronic Allergic Disease-Should We Consider Nutritional Fortification?Nutrients · 2026Article
- Current understanding and future directions in severe asthma through artificial intelligence-integrated multi-omic approaches.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Sex chromosomes and gonadal sex interactions in airway and immune responses to allergen challenge.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Epigenetics in asthma: implications for treatable traits.Frontiers in allergy · 2026Review
- Epidemiology and allergen sensitisation in patients undergoing prick testing.The World Allergy Organization journal · 2025Article
- Non-invasive acoustic classification of adult asthma using an XGBoost model with vocal biomarkers.Scientific reports · 2025Article
- Precision medicine for asthma treatment: Unlocking the potential of the epigenome and microbiome.The Journal of allergy and clinical immunology · 2025Review
- SilencingEnvironmental epigenetics · 2025Article
- NMolecular neurobiology · 2024Article
- Omics approaches in asthma research: Challenges and opportunities.Chinese medical journal pulmonary and critical care medicine · 2024Review
- MicroRNA Profiling of the Inflammatory Response after Early and Late Asthmatic Reaction.International journal of molecular sciences · 2024Article
- The Effects of Environmental Exposure on Epigenetic Modifications in Allergic Diseases.Medicina (Kaunas, Lithuania) · 2024Review
- A review of common influencing factors and possible mechanisms associated with allergic diseases complicating tic disorders in children.Frontiers in pediatrics · 2024Review
- Whole-Genome Bisulfite Sequencing Protocol for the Analysis of Genome-Wide DNA Methylation and Hydroxymethylation Patterns at Single-Nucleotide Resolution.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Dairy intake in association with asthma symptoms among a large sample of children and adolescents: a cross-sectional study.Frontiers in nutrition · 2024Article
- Epigenomic response to albuterol treatment in asthma-relevant airway epithelial cells.Clinical epigenetics · 2023Article
- Novel genetic variants in long non-coding RNA MEG3 are associated with the risk of asthma.PeerJ · 2023Article
- Nasal DNA methylation at three CpG sites predicts childhood allergic disease.Nature communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In asthma and allergy genetics, a trend towards a few main topics developed over the last 2 years. First, a number of studies have been published recently which focus on overlapping and/or very specific phenotypes: within the allergy spectrum but also reaching beyond, looking for common genetic traits shared between different diseases or disease entities. Secondly, an urgently needed focus has been put on asthma and allergy genetics in populations genetically different from European ancestry. This acknowledges that the majority of new asthma patients today are not white and asthma is a truly worldwide disease. In epigenetics, recent years have seen several large-scale epigenome-wide association studies (EWAS) being published and a further focus was on the interaction between the environment and epigenetic signatures. And finally, the major trends in current asthma and allergy genetics and epigenetics comes from the field of pharmacogenetics, where it is necessary to understand the susceptibility for and mechanisms of current asthma and allergy therapies while at the same time, we need to have scientific answers to the recent availability of novel drugs that hold the promise for a more individualized therapy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.