Evidence map›Paper›PMID 32063700›Full record

ArticleClinical interventions in aging2019

Risk Of Urticaria In Geriatric Stroke Patients Who Received Influenza Vaccination: A Retrospective Cohort Study.

Fai Lam, Chun-Chuan Shih, Ta-Liang Chen, Chao-Shun Lin, Hsiao-Ju Huang, Chun-Chieh Yeh, Yu-Chen Huang, Hung-Yi Chiou, Chien-Chang Liao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Fai LamSchool of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0002-3555-7664
Chun-Chuan ShihSchool of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
Ta-Liang ChenDepartment of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chao-Shun LinDepartment of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.ORCID 0000-0001-6964-3862
Hsiao-Ju HuangDevision of Chinese Medicine, An Nan Hospital, China Medical University, Tainan, Taiwan.
Chun-Chieh YehDepartment of Surgery, China Medical University Hospital, Taichung, Taiwan.
Yu-Chen HuangDepartment of Dermatology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Hung-Yi Chiou *School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Chien-Chang Liao *Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.ORCID 0000-0001-6694-0730
China Medical University · TWTaipei Medical University Hospital · TWWan Fang Hospital · TWI-Shou University · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveUrticaria is a mast cell-related disease caused severe itching and the lifetime prevalence of urticaria is about 20% in general population. Our purpose is to evaluate risk of urticaria in geriatric stroke patients received influenza vaccination (IV).

methodsIn a cohort of 192,728 patients with newly diagnosed stroke aged over 65 years obtained from 23 million people in Taiwan's National Health Insurance between 2000 and 2008, we identified 9890 stroke patients who received IV and 9890 propensity score-matched stroke patients who did not receive IV. Controlling for immortal time bias, both the IV and non-IV groups were followed for one year. Urticaria events were identified during the follow-up period. We calculated the adjusted rate ratios (RRs) and 95% confidence intervals (CIs) of the one-year risk of urticaria associated with IV.

resultsDuring the follow-up period of one year, stroke patients with IV had a significantly higher risk of urticaria compared with non-IV stroke patients (RR 1.81, 95% CI 1.47-2.23). An increased risk of urticaria in stroke patients with IV was noted in both sexes, patients 65-84 years of age, patients with comorbid medical conditions, and various time intervals of follow-up. Vaccinated stroke patients with hemorrhage (RR 4.00, 95% CI 1.76-9.10) and those who received intensive care (RR 5.14, 95% CI 2.32-11.4) had a very high risk of urticaria compared with those without IV.

conclusionReceiving IV may be associated with an increased risk of urticaria in stroke patients. We could not infer the causality from the current results because of this study's limitations. Future investigations are needed to evaluate the possible mechanism underlying the association between IV and urticaria.

Indexed as

AgedAged, 80 and overCerebral HemorrhageCritical CareFemaleHumansInfluenza, HumanInfluenza VaccinesMalePropensity ScoreRetrospective StudiesRisk FactorsStrokeTaiwanUrticariaVaccinationInfluenza Vaccinesinfluenza vaccinationstrokeurticaria

Identifiers

PMID32063700
PMCPMC6884998
OpenAlexW2991609273

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.