Evidence map›Paper›PMID 32071905›Full record

ReviewLiver cancer2020

Waist Circumference and Risk of Liver Cancer: A Systematic Review and Meta-Analysis of over 2 Million Cohort Study Participants.

Jamal Rahmani, Hamed Kord Varkaneh, Vasileios Kontogiannis, Paul M Ryan, Hiba Bawadi, Somaye Fatahi, Yong Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Liver cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jamal RahmaniaDepartment of Community Nutrition, Student Research Committee, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hamed Kord VarkanehbStudents' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran, Tehran, Iran.
Vasileios KontogianniscInstitute of Health & Society, Newcastle University, Newcastle upon Tyne, United Kingdom.
Paul M RyandSchool of Medicine, University College Cork, Cork, Ireland.
Hiba BawadieDepartment of Human Nutrition, College of Health Sciences, QU-Health, Qatar University, Doha, Qatar.
Somaye FatahifStudent Research Committee, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Yong ZhanggSchool of Public Health and Health Management, Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLiver cancer is the sixth most common type of cancer worldwide, and waist circumference (WC) is associated with its risk beyond body mass index (BMI). This dose-response meta-analysis was performed to investigate the association between WC and the risk of incident liver cancer using prospective cohort studies.

methodsA comprehensive systematic search was conducted in MEDLINE/PubMed, Web of Science databases, Scopus, and Coch-rane from inception to May 2019. Studies with retrospective or prospective cohort design that reported hazard ratio (HR), risk ratio, or odds ratio, and the corresponding 95% confidence intervals (CI) for liver cancer based on WC categories were included in this meta-analysis. Combined HRs with 95% CIs was estimated by DerSimonian and Laird random-effects models.

resultsAssociations between WC and liver cancer were reported in 5 articles with 2,547,188 participants. All studies were published between 2013 and 2019. Pooled results showed a strong significant association with minimum heterogeneity between WC and risk of liver cancer (HR 1.59, 95% CI 1.38-1.83,

conclusionsThis systematic review and dose-response meta-analysis highlights WC as a significant risk factor related to the incidence of liver cancer.

Indexed as

Central obesityLiver cancerWaist circumference

Identifiers

PMID32071905
PMCPMC7024879

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.