Evidence map›Paper›PMID 32078338›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2020

Atherosclerosis Immunoimaging by Positron Emission Tomography.

Carlos Pérez-Medina, Zahi A Fayad, Willem J M Mulder

Open access · greenAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Cardiovascular imaging with total-body PET.The British journal of radiology · 2026
    Review
  3. Coronary artery disease imaging with total-body PET.The British journal of radiology · 2026
    Review
  4. Review
  5. Can Nuclear Imaging Detect Trained Immunity in Cardiovascular Disease?Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  6. Article
  7. Radiolabeling lipoproteins to study and manage disease.European journal of nuclear medicine and molecular imaging · 2025
    Review
  8. Review
  9. Review
  10. Complex Interplay Between Metabolism and CD4Cardiovascular drugs and therapy · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Non-invasive imaging as the cornerstone of cardiovascular precision medicine.European heart journal. Cardiovascular Imaging · 2022
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Carlos Pérez-MedinaFrom the Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (C.P.-M.).
Zahi A FayadIcahn School of Medicine at Mount Sinai, New York (C.P.-M., Z.A.F., W.J.M.M.).
Willem J M MulderIcahn School of Medicine at Mount Sinai, New York (C.P.-M., Z.A.F., W.J.M.M.).
Icahn School of Medicine at Mount Sinai · USSpanish National Centre for Cardiovascular Research · ES

Funding

Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3M
MR/PET Imaging of coronary atherosclerosisR01HL071021 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI FAYAD, ZAHI A. · 2002 to 2019
$7.8M
Atherosclerosis in cocaine addiction: imaging risk with PET/MRR01DA049547 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Nelly Alia-Klein, Zahi A. Fayad · 2022 to 2026
$3.9M
Studying Atherosclerosis Macrophage Dynamics by Combined PET and Fluorine-MRIR01HL143814 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2019 to 2022
$3.4M
TRAF6 Nanoimmunotherapy to resolve plaque inflammationR01HL144072 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2018 to 2021
$3.3M
Ga68-DOTATATE PET imaging of plaque inflammationR01HL135878 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2017 to 2020
$2.9M
Cardiovascular Inflammation Reduction Trial (CIRT) - Inflammation Imaging StudyR01HL128056 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2015 to 2018
$2.6M
PET/MRI to study nanotherapy in atherosclerosisR01HL125703 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2015 to 2018
$2.4M
Anti-inflammatory nanoparticle formulations to treat atherosclerosisR01HL118440 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM, NAHRENDORF, MATTHIAS · 2014 to 2017
$2.3M
NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL071021NHLBI NIH HHS R01 HL118440NHLBI NIH HHS R01 HL125703NHLBI NIH HHS R01 HL128056NHLBI NIH HHS R01 HL135878NHLBI NIH HHS R01 HL143814NHLBI NIH HHS R01 HL144072NIDA NIH HHS R01 DA049547
6 · The paper itself

Abstract

The immune system's role in atherosclerosis has long been an important research topic and is increasingly investigated for therapeutic and diagnostic purposes. Therefore, noninvasive imaging of hematopoietic organs and immune cells will undoubtedly improve atherosclerosis phenotyping and serve as a monitoring method for immunotherapeutic treatments. Among the available imaging techniques, positron emission tomography's unique features make it an ideal tool to quantitatively image the immune response in the context of atherosclerosis and afford reliable readouts to guide medical interventions in cardiovascular disease. Here, we summarize the state of the art in the field of atherosclerosis positron emission tomography immunoimaging and provide an outlook on current and future applications.

Indexed as

AtherosclerosisHematopoietic SystemHumansNanoparticlesPhagocytesPlaque, AtheroscleroticPositron-Emission TomographyRadioimmunodetectionRadiopharmaceuticalsRadiopharmaceuticalsatherosclerosiscardiovascular diseasesimmune cellsimmune systempositron emission tomography

Identifiers

PMID32078338
PMCPMC7101266
OpenAlexW3004646056

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.