ReviewInternational journal of environmental research and public health2020
The Role of Physical Activity for the Management of Sarcopenia in People Living with HIV.
Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- A systematic review of sarcopenia prevalence and associated factors in people living with human immunodeficiency virus.Journal of cachexia, sarcopenia and muscle · 2023Pooled it
- Combined training improves the diagnostic measures of sarcopenia and decreases the inflammation in HIV-infected individuals.Journal of cachexia, sarcopenia and muscle · 2022Trial
- The Impact of Moderate or High-Intensity Combined Exercise on Systemic Inflammation Among Older Persons With and Without HIV.The Journal of infectious diseases · 2021Trial
- Home-Based Resistance Training for Older Subjects during the COVID-19 Outbreak in Italy: Preliminary Results of a Six-Months RCT.International journal of environmental research and public health · 2020Trial
- Risk of Sarcopenia, Anxiety and Depression Among Healthcare Professionals in Disability Care Facilities.Journal of frailty, sarcopenia and falls · 2026Article
- Geriatric syndromes in women living with HIV.Current opinion in HIV and AIDS · 2026Review
- Vitamin D and physical activity as co-modifiers of muscle health and function - a narrative exploration.Annals of medicine and surgery (2012) · 2025Review
- Prevalence and associated factors related to sarcopenia in people living with HIV/AIDS.BMC infectious diseases · 2024Article
- Design and rationale for a randomized clinical trial testing the efficacy of a lifestyle physical activity intervention for people with HIV and engaged in unhealthy drinking.Contemporary clinical trials · 2024Article
- Article
- Article
- Nutritional and Nutrition-Related Biomarkers as Prognostic Factors of Sarcopenia, and Their Role in Disease Progression.Diseases (Basel, Switzerland) · 2022Review
- Relationship Between Handgrip Strength and Age in the Body Composition Variables Among People Living with HIV.Current HIV research · 2022Article
- Benefits of a 12 week physical activity programme on muscle and bone health in people living with HIV.Journal of cachexia, sarcopenia and muscle · 2021Article
- Efavirenz, atazanavir, and ritonavir disrupt sarcoplasmic reticulum CaAntiviral research · 2021Article
- Sarcopenia: Molecular Pathways and Potential Targets for Intervention.International journal of molecular sciences · 2020Review
- Exercise and COVID-19 as an Infectious Disease.Iranian journal of medical sciences · 2020Article
- Review
- Physical activity among women of low socioeconomic status living with HIV in two major cities of Brazil and Mozambique: A cross-sectional comparative study.Clinics (Sao Paulo, Brazil) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia is a physiopathological process associated with aging, caused by reduction of muscle strength, muscle quality and physical performance, and associated with an increased risk of falls, physical disability and premature death. There is no effective treatment for sarcopenia, but physical exercise seems to be highly effective at counteracting the decline in muscle mass and strength associated with aging. Recently, sarcopenia has been recognized as an emerging issue in people living with HIV (PLWH). Despite adequate treatment with combination antiretroviral therapy (cART), PLWH may exhibit an early occurrence of some aging-related conditions, including sarcopenia, frailty and falls, and this is likely resulting from high rates of comorbidities, high-risk behaviours, chronic immune activation and cART-specific factors. In this review, we discuss the potential mechanisms and the clinical relevance of sarcopenia in PLWH, and present data from longitudinal studies of physical activity in this population. Despite none of these studies having specifically addressed the benefits of physical exercise on sarcopenia, there is evidence that exercise is effective to increase aerobic capacity and muscle strength, and to improve body composition and inflammatory outcomes in PLWH. Therefore, the expected benefits of physical exercise are likely to translate into a successful and specific intervention for prevention and treatment of sarcopenia in this population.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.