Evidence map›Paper›PMID 32083656›Full record

ReviewNucleic acids research2020

DNA nanotechnology assisted nanopore-based analysis.

Taoli Ding, Jing Yang, Victor Pan, Nan Zhao, Zuhong Lu, Yonggang Ke, Cheng Zhang

Abstract readReview
In one paragraph

Review in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
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  15. Cell-Free Expression ofACS nano · 2023
    Article
  16. Review
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  18. Article
  19. Article
  20. Amphiphilic DNA nanostructures for bottom-up synthetic biology.Chemical communications (Cambridge, England) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taoli DingDepartment of Computer Science and Technology, School of Electronics Engineering and Computer Science, Peking University, Beijing 100871, China.
Jing YangSchool of Control and Computer Engineering, North China Electric Power University, Beijing 102206, China.
Victor PanWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Emory University School of Medicine, Atlanta, GA 30322, USA.
Nan ZhaoSchool of Control and Computer Engineering, North China Electric Power University, Beijing 102206, China.
Zuhong LuDepartment of Biomedical Engineering, College of engineering, Peking University, Beijing 100871, China.
Yonggang KeWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Emory University School of Medicine, Atlanta, GA 30322, USA.
Cheng ZhangDepartment of Computer Science and Technology, School of Electronics Engineering and Computer Science, Peking University, Beijing 100871, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanopore technology is a promising label-free detection method. However, challenges exist for its further application in sequencing, clinical diagnostics and ultra-sensitive single molecule detection. The development of DNA nanotechnology nonetheless provides possible solutions to current obstacles hindering nanopore sensing technologies. In this review, we summarize recent relevant research contributing to efforts for developing nanopore methods associated with DNA nanotechnology. For example, DNA carriers can capture specific targets at pre-designed sites and escort them from nanopores at suitable speeds, thereby greatly enhancing capability and resolution for the detection of specific target molecules. In addition, DNA origami structures can be constructed to fulfill various design specifications and one-pot assembly reactions, thus serving as functional nanopores. Moreover, based on DNA strand displacement, nanopores can also be utilized to characterize the outputs of DNA computing and to develop programmable smart diagnostic nanodevices. In summary, DNA assembly-based nanopore research can pave the way for the realization of impactful biological detection and diagnostic platforms via single-biomolecule analysis.

Indexed as

NanoporesAptamers, NucleotideBiosensing TechniquesDNANanotechnologyNucleic Acid ConformationAptamers, NucleotideDNA

Identifiers

PMID32083656
PMCPMC7102975

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.