ReviewTherapeutics and clinical risk management2020
Uric Acid and Arterial Stiffness.
Review in Therapeutics and clinical risk management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Association between exposure to air pollution and arterial stiffness in participants with and without atherosclerotic cardiovascular disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- GPER in metabolic homeostasis and disease: molecular mechanisms, nutritional regulation, and therapeutic potential.Journal of translational medicine · 2025Review
- Shear wave elastography to evaluate the effect of serum uric acid levels on carotid artery elasticity in patients with high-normal blood pressure.Journal of medical biochemistry · 2025Article
- Association of homocysteine and uric acid with type 2 diabetes mellitus: a case-control study.Scientific reports · 2025Article
- Combined predictive value of uric acid and serum lipid for stroke events in non-valvular atrial fibrillation patients.Frontiers in cardiovascular medicine · 2025Article
- High levels of uric acid upregulate endothelin receptors: the role of MAPK pathways in anArchives of medical science : AMS · 2025Article
- Assessing the role of dietary acid load in the development of hypertensive disorders during pregnancy: uncovering the association through prospective cohort analysis.Nutrition journal · 2024Article
- THE EFFECT OF URIC ACID LEVEL ON THE SEVERITY OF COVID-19.Acta clinica Croatica · 2024Article
- High serum uric acid is a risk factor for arterial stiffness in a Chinese hypertensive population: a cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Extrahepatic Vitamin K-Dependent Gla-Proteins-Potential Cardiometabolic Biomarkers.International journal of molecular sciences · 2024Review
- 4,5-Diamino-2-Thiouracil-Powered Dual-Mode Biosensor for Sensitive, Nonenzymatic Determination of Saliva Uric Acid Levels.International journal of analytical chemistry · 2024Article
- Association of gout with brain reserve and vulnerability to neurodegenerative disease.Nature communications · 2023Article
- Insights into SGLT2 inhibitor treatment of diabetic cardiomyopathy: focus on the mechanisms.Cardiovascular diabetology · 2023Review
- Arterial stiffness and biological parameters: A decision tree machine learning application in hypertensive participants.PloS one · 2023Article
- Wuling San Based on Network Pharmacology and in vivo Evidence Against Hyperuricemia via Improving Oxidative Stress and Inhibiting Inflammation.Drug design, development and therapy · 2023Article
- Mutual effect of homocysteine and uric acid on arterial stiffness and cardiovascular risk in the context of predictive, preventive, and personalized medicine.The EPMA journal · 2022Article
- Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females.Journal of atherosclerosis and thrombosis · 2022Article
- Article
- Metabolomics of Arterial Stiffness.Metabolites · 2022Review
- Inflammaging and Vascular Function in Metabolic Syndrome: The Role of Hyperuricemia.Medicina (Kaunas, Lithuania) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperuricemia is usually associated with hypertension, diabetes mellitus, metabolic syndrome and chronic kidney disease. Accumulating data from epidemiological studies indicate an association of increased uric acid (UA) with cardiovascular diseases. Possible pathogenic mechanisms include enhancement of oxidative stress and systemic inflammation caused by hyperuricemia. Arterial stiffness may be one of the possible pathways between hyperuricemia and cardiovascular disease, but a clear relationship between increased UA and vascular alterations has not been confirmed. The review summarizes the epidemiological studies investigating the relationship between UA and arterial stiffness and highlights the results of interventional studies evaluating arterial stiffness parameters in patients treated with UA-lowering drugs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.