Evidence map›Paper›PMID 32099355›Full record

ArticleInternational journal of nanomedicine2020

Prostate Cancer Cellular Uptake of Ternary Titanate Nanotubes/CuFe

Ahmed Ag El-Shahawy, S A Abdel Moaty, A H Zaki, Nada A Mohamed, Yasser GadelHak, R K Mahmoud, A A Farghali

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ahmed Ag El-ShahawyMaterials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, Egypt.
S A Abdel MoatyChemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0002-2462-2037
A H ZakiMaterials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, Egypt.
Nada A MohamedChemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0003-2274-2016
Yasser GadelHakMaterials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0001-5186-160X
R K MahmoudChemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.
A A FarghaliMaterials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, Egypt.
Beni-Suef University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCertainly, there is a demand for stronger recognition of how nanoparticles can move through the cell membrane. Prostate cancer is one of the forcing sources of cancer-relevant deaths among men. AIM OF THE WORK: The current research studied the power of prostate cancer cells to uptake a ternary nanocomposite TNT/CuFe METHODOLOGY: The nanocomposite was synthesized by a chemical method and characterized by a High-resolution transmission electron microscope, Field emission scanning electron microscope, X-ray diffraction, Fourier transmission infra-red, X-ray photoelectron spectroscopy, dynamic light scattering. Besides, it was implemented as an inorganic anticancer agent versus Prostate cancer PC-3 cells.

resultsThe results revealed cellular uptake validity, cell viability reduction, ultra-structures alterations, morphological changes and membrane damage of PC-3 cells.

conclusionThe prepared ternary nanocomposite was highly uptake by PC-3 cells and possessed cytotoxicity that was dose and time-dependent. To conclude, the study offered the potential of the investigated ternary nanocomposite as a promising prostate anticancer agent.

Indexed as

Antineoplastic AgentsCell Line, TumorCell SurvivalCopperDynamic Light ScatteringHumansIronMaleMicroscopy, Electron, TransmissionNanocompositesNanotubesOxidesPhotoelectron SpectroscopyProstatic NeoplasmsTitaniumX-Ray DiffractionAntineoplastic AgentsCopperIronOxidesTitaniumZinccytotoxicityinorganic nanomaterialsprostate cancer

Identifiers

PMID32099355
PMCPMC6996550
OpenAlexW3004415074

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.