ReviewPulmonary circulation
The changing face of pulmonary hypertension diagnosis: a historical perspective on the influence of diagnostics and biomarkers.
Review in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Cardiopulmonary transit time measured on dynamic rubidium cardiac PET/CT is a predictor for pulmonary hypertension.EJNMMI research · 2026Article
- Quantitative CT Pulmonary Angiography and Echo Cardiography Analysis for Enhanced Cardiovascular Assessment of Right Ventricular Failure in Pulmonary Hypertension.International journal of general medicine · 2026Article
- Identification of plasma tRNA-derived small RNA i-tRF-15:31-Lys-CTT-1 as a biomarker for diagnosis and prognosis of pulmonary arterial hypertension.Non-coding RNA research · 2025Article
- Hemodynamic Definitions, Phenotypes, Pathophysiology, and Evaluation of Pulmonary Hypertension Related to Left Heart Disease.Journal of cardiovascular development and disease · 2025Review
- A Prospective Analysis of Vasoreactivity and Mortality in WHO Group 3 Pulmonary Hypertension.Pulmonary circulation · 2025Article
- Pulmonary Hypertension: Pharmacological and Non-Pharmacological Therapies.Life (Basel, Switzerland) · 2024Review
- Novel Hemodynamic, Vascular Lesion, and Cytokine/Chemokine Differences Regarding Sex in a Pulmonary Arterial Hypertension Model.American journal of respiratory cell and molecular biology · 2024Article
- Extracellular cAMP: The Past and Visiting the Future in cAMP-Enriched Extracellular Vesicles.Advanced biology · 2021Article
- Review
- CCR7 and its related molecules may be potential biomarkers of pulmonary arterial hypertension.FEBS open bio · 2021Article
- Pre- and postcapillary pulmonary hypertension in dogs: Circulating biomarkers.Open veterinary journalArticle
- Circulating nerve growth factor receptor positive cells are associated with severity and prognosis of pulmonary arterial hypertension.Pulmonary circulationArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Pulmonary hypertension is a complex, multifactorial disease that results in right heart failure and premature death. Since the initial reports of pulmonary hypertension in the late 1800s, the diagnosis of pulmonary hypertension has evolved with respect to its definition, screening tools, and diagnostic techniques. This historical perspective traces the earliest roots of pulmonary hypertension detection and diagnosis through to the current recommendations for classification. We highlight the diagnostic tools used in the past and present, and end with a focus on the future directions of early detection. Early detection of pulmonary hypertension and pulmonary arterial hypertension and the proper determination of etiology are vital for the early therapeutic intervention that can prolong life expectancy and improve quality of life. The search for a non-invasive screening tool for the identification and classification of pulmonary hypertension is ongoing, and we discuss the role of animal models of the disease in this search.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.