Evidence map›Paper›PMID 32121184›Full record

Trial reportNutrients2020

A Regionalized Genome-Based Mexican Diet Improves Anthropometric and Metabolic Parameters in Subjects at Risk for Obesity-Related Chronic Diseases.

Claudia Ojeda-Granados, Arturo Panduro, Ingrid Rivera-Iñiguez, Maricruz Sepúlveda-Villegas, Sonia Roman

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Claudia Ojeda-GranadosDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara "Fray Antonio Alcalde," Hospital #278, Col. El Retiro, Guadalajara 44280, Jalisco, Mexico.
Arturo PanduroDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara "Fray Antonio Alcalde," Hospital #278, Col. El Retiro, Guadalajara 44280, Jalisco, Mexico.
Ingrid Rivera-IñiguezDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara "Fray Antonio Alcalde," Hospital #278, Col. El Retiro, Guadalajara 44280, Jalisco, Mexico.
Maricruz Sepúlveda-VillegasDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara "Fray Antonio Alcalde," Hospital #278, Col. El Retiro, Guadalajara 44280, Jalisco, Mexico.
Sonia RomanDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara "Fray Antonio Alcalde," Hospital #278, Col. El Retiro, Guadalajara 44280, Jalisco, Mexico.
Universidad de Guadalajara · MX

Funding

PRODEP CA478
6 · The paper itself

Abstract

Obesity-related chronic diseases (CD) are highly prevalent in Mexicans who show moderate to high frequencies of diet-related adaptive gene (DRAG) polymorphisms and recent shifts in traditional dietary habits and lifestyles. This study first evaluated the effects of a regionalized genome-based Mexican (GENOMEX) diet on anthropometric and biochemical parameters and, subsequently their relationship with the genetic profile of DRAG polymorphisms in subjects with metabolic risk factors for obesity-related CD. Thirty-seven eligible subjects underwent a 24-week dietary intervention with a GENOMEX diet. The DRAG polymorphisms were determined by an allelic discrimination real-time assay to evaluate their association with the clinical response to diet. The GENOMEX diet significantly improved anthropometric parameters such as total weight, body mass index, waist circumference, and body fat percentage, with an average weight loss of 6.6% (5.3 ± 5.3 kg). The frequency of subjects with insulin resistance, hypertriglyceridemia and elevated VLDL-c (48.5% vs. 24.2%,

Indexed as

Diet, ReducingGenome, HumanAdultAnthropometryChronic DiseaseFemaleHomeostasisHumansInsulinInsulin ResistanceMaleMexicoObesityPolymorphism, GeneticRisk FactorsInsulinadaptive genesgenome-based nutritioninsulin resistancelipidsmetabolic diseasesnutrigeneticsobesityoverweightstaple foodstraditional Mexican diet

Identifiers

PMID32121184
PMCPMC7146143
OpenAlexW3009275090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.