Evidence map›Paper›PMID 32143448›Full record

ArticleMaterials (Basel, Switzerland)2020

Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages.

Tobias Schmitz, Maren Jannasch, Tobias Weigel, Claus Moseke, Uwe Gbureck, Jürgen Groll, Heike Walles, Jan Hansmann

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tobias SchmitzDepartment Tissue Engineering and Regenerative Medicine (TERM), University Hospital, 97070 Würzburg, Germany.
Maren JannaschDepartment Tissue Engineering and Regenerative Medicine (TERM), University Hospital, 97070 Würzburg, Germany.
Tobias WeigelDepartment Tissue Engineering and Regenerative Medicine (TERM), University Hospital, 97070 Würzburg, Germany.
Claus MosekeInstitute for Biomedical Engineering (IBMT), University of Applied Sciences Mittelhessen (THM), 35390 Gießen, Germany.
Uwe GbureckDepartment of Functional Materials in Medicine and Dentistry (FMZ), University Hospital, 97070 Würzburg, Germany.
Jürgen GrollDepartment of Functional Materials in Medicine and Dentistry (FMZ), University Hospital, 97070 Würzburg, Germany.
Heike WallesCore Facility Tissue Engineering, Otto von Guericke University, 39106 Magdeburg, Germany.
Jan HansmannDepartment Tissue Engineering and Regenerative Medicine (TERM), University Hospital, 97070 Würzburg, Germany.

Funding

Bundesministerium für Bildung und Forschung 13N12971
6 · The paper itself

Abstract

Implants elicit an immunological response after implantation that results in the worst case in a complete implant rejection. This biomaterial-induced inflammation is modulated by macrophages and can be influenced by nanotopographical surface structures such as titania nanotubes or fractal titanium nitride (TiN) surfaces. However, their specific impact on a distinct macrophage phenotype has not been identified. By using two different levels of nanostructures and smooth samples as controls, the influence of tubular TiO

Indexed as

combination of physical vapor deposition and electrochemical etchingdefined humanized test systeminflammatory responsenanotopographical surfaces

Identifiers

PMID32143448
PMCPMC7084960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.