Trial reportDiabetes care2020
The Use of a Smart Bolus Calculator Informed by Real-time Insulin Sensitivity Assessments Reduces Postprandial Hypoglycemia Following an Aerobic Exercise Session in Individuals With Type 1 Diabetes.
Trial report in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03709108 (Safety and Feasibility of an Insulin Sensitivity-Informed Bolus Calculator in Type 1 Diabetes), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Feasibility of an Insulin Sensitivity-Informed Bolus Calculator in Type 1 Diabetes
Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Toward Personalized Decision Support Systems for Type 1 Diabetes: Integrating Psychobehavioral Factors and Glycemic Control.Journal of diabetes science and technology · 2025Trial
- Separating insulin-mediated and non-insulin-mediated glucose uptake during and after aerobic exercise in type 1 diabetes.American journal of physiology. Endocrinology and metabolism · 2021Trial
- Use of Continuous Glucose Monitors in Exercise Research Studies-A Scoping Review on Study Characteristics and Common Practices.Sports (Basel, Switzerland) · 2026Review
- Enhancing the Capabilities of Continuous Glucose Monitoring With a Predictive App.Journal of diabetes science and technology · 2024Article
- Continuous Glucose Monitoring and Bolus Calculators: A Good Combination.Journal of diabetes science and technology · 2024Article
- Performance Effect of Adjusting Insulin Sensitivity for Model-Based Automated Insulin Delivery Systems.Journal of diabetes science and technology · 2023Article
- Clinical Evaluation of a Novel CGM-Informed Bolus Calculator with Automatic Glucose Trend Adjustment.Diabetes technology & therapeutics · 2022Article
- Simulation-Based Evaluation of Treatment Adjustment to Exercise in Type 1 Diabetes.Frontiers in endocrinology · 2021Article
- Artificial Intelligence in Decision Support Systems for Type 1 Diabetes.Sensors (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveInsulin dosing in type 1 diabetes (T1D) is oftentimes complicated by fluctuating insulin requirements driven by metabolic and psychobehavioral factors impacting individuals' insulin sensitivity (IS). In this context, smart bolus calculators that automatically tailor prandial insulin dosing to the metabolic state of a person can improve glucose management in T1D. RESEARCH DESIGN AND
methodsFifteen adults with T1D using continuous glucose monitors (CGMs) and insulin pumps completed two 24-h admissions in a hotel setting. During the admissions, participants engaged in an early afternoon 45-min aerobic exercise session, after which they received a standardized dinner meal. The dinner bolus was computed using a standard bolus calculator or smart bolus calculator informed by real-time IS estimates. Glucose control was assessed in the 4 h following dinner using CGMs and was compared between the two admissions.
resultsThe IS-informed bolus calculator allowed for a reduction in postprandial hypoglycemia as quantified by the low blood glucose index (2.02 vs. 3.31,
conclusionsThe study shows that the proposed IS-informed bolus calculator is safe and feasible in adults with T1D, appropriately reducing postprandial hypoglycemia following an exercise-induced IS increase.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.