Evidence map›Paper›PMID 32152513›Full record

Trial reportEuropean journal of clinical nutrition2020

Effects of substituting eggs for high-carbohydrate breakfast foods on the cardiometabolic risk-factor profile in adults at risk for type 2 diabetes mellitus.

Kevin C Maki, Orsolya M Palacios, Melvyn W Kramer, Rupal Trivedi, Mary R Dicklin, Meredith L Wilcox, Cathleen E Maki

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 5 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 5 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Review
  8. Article
  9. Nutritional Viewpoints on Eggs and Cholesterol.Foods (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kevin C MakiMidwest Biomedical Research, Addison, IL, USA. kmaki@mbclinicalresearch.com.
Orsolya M PalaciosMidwest Biomedical Research, Addison, IL, USA.
Melvyn W KramerMB Clinical Research, Boca Raton, FL, USA.
Rupal TrivediGreat Lakes Clinical Trials, Chicago, IL, USA.
Mary R DicklinMidwest Biomedical Research, Addison, IL, USA.
Meredith L WilcoxMB Clinical Research, Boca Raton, FL, USA.
Cathleen E MakiMidwest Biomedical Research, Addison, IL, USA.
Great Lakes Clinical Trials · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess effects of egg-based versus non-egg, higher-carbohydrate (CHO) breakfast meals on cardiometabolic health markers in overweight or obese adults with prediabetes and/or metabolic syndrome.

methodsThis randomized, crossover study included two 4-week dietary interventions, separated by a ≥4-week washout. Subjects incorporated into their habitual diets breakfast meals containing either 2 eggs/day for 6 days/week (Egg condition), or energy-matched, non-egg, higher-CHO-based foods (Non-Egg condition). Dietary intakes, insulin sensitivity, and other CHO metabolism indices, lipid biomarkers, high-sensitivity C-reactive protein, and blood pressures were measured.

resultsThirty men and women with mean age 54.1 ± 1.9 years and body mass index 31.9 ± 0.7 kg/m

conclusionCompared with the baseline diet, consumption of 12 eggs/week for 4 weeks at breakfast was associated with less reduction in LDL-C, and more lowering of systolic blood pressure, than observed with non-egg-based, energy-matched, control foods higher in CHO.

Indexed as

BreakfastEggsCardiovascular DiseasesCross-Over StudiesDiabetes Mellitus, Type 2Dietary CarbohydratesFemaleHumansMaleMiddle AgedDietary Carbohydrates

Identifiers

PMID32152513
PMCPMC7214271
OpenAlexW3010307621

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.