ArticleJournal of clinical hypertension (Greenwich, Conn.)2020
Central rather than brachial pressures are stronger predictors of cardiovascular outcomes: A longitudinal prospective study in a Chinese population.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Association of cardiovascular events with central systolic blood pressure: A systemic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2024Pooled it
- Twenty-Four-Hour Central Ambulatory Blood Pressure: Relationship With Measures of Cardiovascular Subclinical Organ Damage in Healthy Individuals.Journal of the American Heart Association · 2026Article
- Effects of at-risk drinking on central hemodynamics and aortic stiffness in midlife adults.Physiological reports · 2026Article
- Arterial Stiffness, Central Blood Pressure, and the Risk of Incident Stroke in Hypertensive Adults.European journal of neurology · 2025Article
- Independent and joint effect of central and brachial SBP on incident stroke in hypertensive adults.Journal of hypertension · 2025Article
- Genetic variation in CCDC93 is associated with elevated central systolic blood pressure, impaired arterial relaxation, and mitochondrial dysfunction.PLoS genetics · 2024Article
- CENtral blood pressure Targeting: a pragmatic RAndomized triaL in advanced Chronic Kidney Disease (CENTRAL-CKD): A Clinical Research Protocol.Canadian journal of kidney health and disease · 2023Article
- Resting heart rate (variability) and cognition relationships reveal cognitively healthy individuals with pathological amyloid/tau ratio.Frontiers in epidemiology · 2023Article
- Positive association between triglyceride glucose index and central systolic blood pressure among hypertensive adults.Journal of geriatric cardiology : JGC · 2022Article
- Indoor air quality and the risk of hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Accuracy Difference of Noninvasive Blood Pressure Measurements by Sex and Height.JAMA network open · 2022Article
- Enhancing central blood pressure accuracy through statistical modeling: A proof-of-concept study.Frontiers in cardiovascular medicine · 2022Article
- Prediction of Cardiovascular Events by Type I Central Systolic Blood Pressure: A Prospective Study.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Blood pressure measurements-Shifting the focus from periphery to center.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Central rather than brachial pressures are stronger predictors of cardiovascular outcomes: A longitudinal prospective study in a Chinese population.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
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Authors and funding
40 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to assess the association of blood pressure (BP) measurements with the risk of cardiovascular disease (CVD) and examine whether central systolic BP (CSBP) predicts CVD better than brachial BP measurements (SBP and pulse pressure [PP]). Based on a cross-sectional study conducted in 2009-2010 with follow-up in 2016-2017 among 35- to 64-year-old subjects in China, we evaluated the performance of non-invasively predicted CSBP over brachial BP measurements on the first CVD events. Each BP measurement, individually and jointly with another BP measurement, was entered into the multivariate Cox proportional-hazards models, to examine the predictability of central and brachial BP measurements. Mean age of participants (n = 8710) was 50.1 years at baseline. After a median follow-up of 6.36 years, 187 CVD events occurred. CSBP was a stronger predictor for CVD than brachial BP measurements (CSBP, 1-standard deviation increment HR = 1.49, 95%CI: 1.31-1.70). With CSBP and SBP entering into models jointly, the HR for CSBP and SBP was 1.28 (1.04-1.58) and 1.22 (0.98-1.50), respectively. With CSBP and PP entering into models jointly, the HR for CSBP and PP was 1.51 (1.28-1.78) and 0.98 (0.83-1.15), respectively. For subgroup analysis, the association of CSBP with CVD was stronger than brachial BP measurements in women, those with hypertension and obesity. In the middle-aged Chinese population, noninvasively estimated CSBP may offer advantages over brachial BP measurements to predict CVD events, especially for participants with higher risk. These findings suggest prospective assessment of CSBP as a prevention and treatment target in further trials.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.