Evidence map›Paper›PMID 32153736›Full record

ArticleAvicenna journal of medical biotechnology

Effect of Poly-Histidine Tag Position toward Inhibition Activity of Secretory Leukocyte Protease Inhibitor as Candidate for Material Wound Healing.

Elly Munadziroh, Evi Umayah Ulfa, Amaliah Labiqah, One Asmarani, Ni Nyoman Tri Puspaningsih

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biomolecules · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elly MunadzirohDepartment of Dental Material and Technology, Faculty of Dentistry, Universitas Airlangga, Surabaya, Indonesia.
Evi Umayah UlfaDepartment of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Jember, Jember, Indonesia.
Amaliah LabiqahDepartment of Health Analysis, Stikes Kesetiakawanan Sosial Indonesia, Jakarta, Indonesia.
One AsmaraniProteomic Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia.
Ni Nyoman Tri PuspaningsihDepartment of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Secretory Leukocyte Protease Inhibitors (SLPI) has many biological functions including anti-bacterial, anti-fungal, anti-viral, anti-inflammatory, and immuno-modulatory. Previous studies have shown that gene-encoding human SLPI have successfully been expressed in

methodsA NSLPI and CSLPI were constructed with polymerase chain reaction (PCR) amplification. The PCR products were then ligated into pET-30a plasmid and transformed into

resultsThe SLPI gene was successfully cloned and expressed in

conclusionThe His-tag position on the C-terminal of SLPI reduced the inhibition activity of SLPI.

Indexed as

Escherichia coliGene expressionPoly histidineSecretory leukocyte protease inhibitor

Identifiers

PMID32153736
PMCPMC7035463

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.